Evidence map›Paper›PMID 31441090›Full record

SynthesisDiabetic medicine : a journal of the British Diabetic Association2019

Risk scores for type 2 diabetes mellitus in Latin America: a systematic review of population-based studies.

R M Carrillo-Larco, D J Aparcana-Granda, J R Mejia, N C Barengo, A Bernabe-Ortiz

Abstract readSystematic Review
In one paragraph

Synthesis in Diabetic medicine : a journal of the British Diabetic Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Risk scores for type 2 diabetes mellitus in Latin America: a systematic review of population-based studies.Diabetic medicine : a journal of the British Diabetic Association · 2019
    Pooled it
  4. Article
  5. Article
  6. Observational
  7. Review
  8. Article
  9. Article
  10. Development and Validation of a New Diabetes Risk Score in Guyana.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2020
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

R M Carrillo-LarcoDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.ORCID 0000-0002-2090-1856
D J Aparcana-GrandaCRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Perú.
J R MejiaFacultad de Medicina Humana, Universidad Nacional del Centro del Perú, Huancayo, Perú.
N C BarengoDepartment of Medical and Population Health Sciences Research, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, USA.
A Bernabe-OrtizCRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Perú.ORCID 0000-0002-6834-1376

Funding

Wellcome TrustWellcome Trust 100693/Z/12/ZWellcome Trust 214185/Z/18/ZWellcome Trust 294834/Z/16/Z
6 · The paper itself

Abstract

aimTo summarize the evidence on diabetes risk scores for Latin American populations.

methodsA systematic review was conducted (CRD42019122306) looking for diagnostic and prognostic models for type 2 diabetes mellitus among randomly selected adults in Latin America. Five databases (LILACS, Scopus, MEDLINE, Embase and Global Health) were searched. type 2 diabetes mellitus was defined using at least one blood biomarker and the reports needed to include information on the development and/or validation of a multivariable regression model. Risk of bias was assessed using the PROBAST guidelines.

resultsOf the 1500 reports identified, 11 were studied in detail and five were included in the qualitative analysis. Two reports were from Mexico, two from Peru and one from Brazil. The number of diabetes cases varied from 48 to 207 in the derivations models, and between 29 and 582 in the validation models. The most common predictors were age, waist circumference and family history of diabetes, and only one study used oral glucose tolerance test as the outcome. The discrimination performance across studies was ~ 70% (range: 66-72%) as per the area under the receiving-operator curve, the highest metric was always the negative predictive value. Sensitivity was always higher than specificity.

conclusionThere is no evidence to support the use of one risk score throughout Latin America. The development, validation and implementation of risk scores should be a research and public health priority in Latin America to improve type 2 diabetes mellitus screening and prevention.

Indexed as

AdultAge FactorsBrazilDiabetes Mellitus, Type 2FemaleGlucose Tolerance TestHumansLatin AmericaMaleMedical History TakingMEDLINEMexicoMiddle AgedPeruPrognosisReproducibility of Results

Identifiers

PMID31441090
PMCPMC6900051

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.