SynthesisJournal of assisted reproduction and genetics2019
Risk of adverse perinatal outcomes after oocyte donation: a systematic review and meta-analysis.
Synthesis in Journal of assisted reproduction and genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Assisted Reproductive Technology as Predictor for Preeclampsia: A Systematic Review of Current Clinical Prediction Models.Reproductive sciences (Thousand Oaks, Calif.) · 2026Pooled it
- The risk for the development of hypertensive complications in oocyte donation pregnancy: a systematic review and individual participant data meta-analysis (DONOR IPD).Human reproduction update · 2026Pooled it
- Maternal and perinatal complications according to maternal age: A systematic review and meta-analysis.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2022Pooled it
- Spontaneous Premature Ovarian Insufficiency: Methods Under Research for Infertility Treatment.Journal of clinical medicine · 2026Review
- Perinatal outcomes in pregnancies with very and extremely advanced maternal age: An Italian multicenter retrospective cohort study.Acta obstetricia et gynecologica Scandinavica · 2026Article
- High-Risk Outcomes in In Vitro Fertilization Pregnancies for Women of a Very Advanced Maternal Age: Insights from a Multi-Hospital Study in Greece.Journal of clinical medicine · 2025Article
- Stringent Regulations of Oocyte Donation Among Jewish Women in Israel: Characteristics and Outcomes of the National Oocyte Donation Program in One Central IVF Unit.Journal of religion and health · 2025Article
- Sirtuins and Their Implications in the Physiopathology of Gestational Diabetes Mellitus.Pharmaceuticals (Basel, Switzerland) · 2025Review
- [Obstetric and neonatal outcomes in pregnancies conceived by assisted reproductive technology in an Argentine cohort]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2024Article
- Perinatal Outcomes of Singleton, Twin and Triplet Gestations after Oocyte Donation: A Retrospective, Population-Based Cohort Analysis.Children (Basel, Switzerland) · 2024Article
- Article
- Pathologic maternal and neonatal outcomes associated with programmed embryo transfer: potential etiologies and strategies for prevention.Journal of assisted reproduction and genetics · 2024Review
- Pathologic maternal and neonatal outcomes associated with programmed embryo transfer.Journal of assisted reproduction and genetics · 2024Review
- Pregnancies through oocyte donation. A mini review of pathways involved in placental dysfunction.Frontiers in medicine · 2024Review
- Comparison of obstetric and perinatal complications in intracytoplasmic sperm injection cycles with autologous oocytes and donated oocytes.Revista da Associacao Medica Brasileira (1992) · 2024Article
- Perinatal outcomes in 6640 singleton pregnancies after donor oocyte IVF across three continents over 7 years.Journal of assisted reproduction and genetics · 2023Article
- Elevated Sperm DNA Damage in IVF-ICSI Treatments Is Not Related to Pregnancy Complications and Adverse Neonatal Outcomes.Journal of clinical medicine · 2023Article
- Increased Risk of Preeclampsia with Assisted Reproductive Technologies.Current hypertension reports · 2023Review
- Pregnancy outcome and follow-up of offspring of donor oocytes recipient from PCOS patients.BMC pregnancy and childbirth · 2022Article
- Lifting the veil of secrecy: maternal and neonatal outcome of oocyte donation pregnancies in Germany.Archives of gynecology and obstetrics · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
research questionIn women with singleton pregnancies conceived after assisted reproductive technologies, does the in vitro fertilization with oocyte donation (IVF-OD) affect the perinatal and maternal outcomes compared to autologous in vitro fertilization (IVF-AO)?
designSystematic review and meta-analysis of studies comparing perinatal and maternal outcomes in singleton pregnancies resulting from IVF-OD versus IVF-AO. An electronic literature search in Pubmed, MEDLINE, and Cochrane database was performed. The main outcome measures were hypertensive disorders in pregnancy, preeclampsia, severe preeclampsia, pregnancy-induced hypertension, preterm birth, early preterm birth, low birth weight, and very low birth weight.
resultsTwenty-three studies were included. IVF-OD is associated with a higher risk of hypertensive disorders in pregnancy (OR 2.63, 2.17-3.18), preeclampsia (OR 2.64; 2.29-3.04), severe preeclampsia (OR 3.22; 2.30-4.49), pregnancy-induced hypertension (OR 2.16; 1.79-2.62), preterm birth (OR 1.57; 1.33-1.86), early preterm birth (OR 1.80; 1.51-2.15), low birth weight (OR 1.25, 1.20-1.30), very low birth weight (OR 1.37, 1.22-1.54), gestational diabetes (OR 1.27; 1.03-1.56), and cesarean section (OR 2.28; 2.14-2.42). There was no significant difference in the risk of preterm birth or low birth weight when adjusted for preeclampsia.
conclusionsIVF-OD patients should be considered an independent risk factor for some adverse perinatal outcomes, mainly hypertensive disorders in pregnancy, preeclampsia, and severe preeclampsia. Immunological and hormonal aspects may be involved in these results, and further research focusing in the etiopathogenesis of these pathologies are needed.
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