ArticleMikrochimica acta2019
A nanocomposite prepared from metal-free mesoporous carbon nanospheres and graphene oxide for voltammetric determination of doxorubicin.
Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 28 citations in OpenAlex.
- Recent trends in mesoporous carbon-based nanoplatforms for biomedical application.Journal of pharmaceutical analysis · 2025Review
- Nanoenzyme-based sensors for the detection of anti-tumor drugs.Mikrochimica acta · 2025Review
- Mesoporous Carbon Composites Containing Carbon Nanostructures: Recent Advances in Synthesis and Applications in Electrochemistry.Materials (Basel, Switzerland) · 2024Review
- Voltammetric Sensor for Doxorubicin Determination Based on Self-Assembled DNA-Polyphenothiazine Composite.Nanomaterials (Basel, Switzerland) · 2023Article
- Impedimetric DNA Sensor Based on Electropolymerized N-Phenylaminophenothiazine and Thiacalix[4]arene Tetraacids for Doxorubicin Determination.Biosensors · 2023Article
- Electrochemical DNA Sensor Based on Acridine Yellow Adsorbed on Glassy Carbon Electrode.Sensors (Basel, Switzerland) · 2021Article
- Electrochemical DNA Sensor Based on the Copolymer of Proflavine and Azure B for Doxorubicin Determination.Nanomaterials (Basel, Switzerland) · 2020Article
- Construction of a sensitive electrochemical sensor based on 1T-MoSMikrochimica acta · 2020Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
A metal-free catalyst is described that consists of a composite that can be prepared from mesoporous carbon spheres (MCS) and graphene oxide (GO) under mild aqueous synthetic conditions. The reduced graphene oxide (rGO) sheets tend to aggregate, but due to the insertion of MCS, the aggregation is prevented. This leads to a larger surface area and more adsorption sites for the cancer drug doxorubicin (DOX). The π-interaction between DOX and rGO is also beneficial for the adsorption of DOX. A glassy carbon electrode (GCE) was modified with the composite and used to detect low levels of DOX, typically at a peak potential near -0.45 V (vs. Ag/AgCl). The modified GCE has a wide linear response range (10 nM - 10 μM), a low limit of detection (1.5 nM; at S/N = 3), excellent selectivity, long-term storage stability and reproducibility. It was applied to the determination of DOX in spiked serum where it gave reliable results. Graphical abstract Schematic representation of the preparation of mesoporous carbon spheres/reduced graphene oxide (MCS/rGO) sample, and the CV scan of doxorubicin (DOX) on MCS/rGO based nanoprode.
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