Evidence map›Paper›PMID 31440778›Full record

SynthesisWorld journal of surgery2019

Laparoscopic Versus Open Complete Mesocolon Excision in Right Colon Cancer: A Systematic Review and Meta-Analysis.

Mohamed Ali Chaouch, Mohamed Wejih Dougaz, Ibtissem Bouasker, Hichem Jerraya, Wafa Ghariani, Mehdi Khalfallah, Ramzi Nouira, Chadli Dziri

Abstract readComparative StudyMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in World journal of surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 11 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 11 syntheses or guidelines pooled it, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mohamed Ali ChaouchDepartment B of Surgery, Charles Nicolle Hospital, Tunis, Tunisia. Docmedalichaouch@gmail.com.ORCID 0000-0002-9013-5229
Mohamed Wejih DougazDepartment B of Surgery, Charles Nicolle Hospital, Tunis, Tunisia.
Ibtissem BouaskerDepartment B of Surgery, Charles Nicolle Hospital, Tunis, Tunisia.
Hichem JerrayaDepartment B of Surgery, Charles Nicolle Hospital, Tunis, Tunisia.
Wafa GharianiDepartment B of Surgery, Charles Nicolle Hospital, Tunis, Tunisia.
Mehdi KhalfallahDepartment B of Surgery, Charles Nicolle Hospital, Tunis, Tunisia.
Ramzi NouiraDepartment B of Surgery, Charles Nicolle Hospital, Tunis, Tunisia.
Chadli DziriDepartment B of Surgery, Charles Nicolle Hospital, Tunis, Tunisia.
Hôpital Charles-Nicolle · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaparoscopic complete mesocolon excision (LCME) for right colonic cancer improves oncological outcomes. This systematic review and meta-analysis aimed to compare intraoperative, postoperative, and oncological outcomes after LCME and open total mesocolon excision (OCME) for right-sided colonic cancers.

methodsLiterature searches of electronic databases and manual searches up to January 31, 2019, were performed. Random-effects meta-analysis model was used. Review Manager Version 5.3 was used for pooled estimates.

resultsAfter screening 1334 articles, 10 articles with a total of 2778 patients were eligible for inclusion. Compared to OCME, LCME improves results in terms of overall morbidity (OR = 1.48, 95% CI 1.21 to 1.80, p = 0.0001), blood loss (MD = 56.56, 95% CI 19.05 to 94.06, p = 0.003), hospital stay (MD = 2.18 day, 95% CI 0.54 to 3.83, p = 0.009), and local (OR = 2.12, 95% CI 1.09 to 4.12, p = 0.03) and distant recurrence (OR = 1.63, 95% CI 1.23-2.16, p = 0.0008). There was no significant difference regarding mortality, anastomosis leakage, number of harvested lymph nodes, and 3-year disease-free survival. Open approach was significantly better than laparoscopy in terms of operative time (MD = - 34.76 min, 95% CI - 46.01 to - 23.50, p < 0.00001) and chyle leakage (OR = 0.41, 95% CI 0.18 to 0.96, p = 0.04).

conclusionsThis meta-analysis suggests that LCME in right colon cancer surgery is superior to OCME in terms of overall morbidity, blood loss, hospital stay, and local and distant recurrence with a moderate grade of recommendation due to the retrospective nature of the included studies.

Indexed as

Colonic NeoplasmsFemaleHumansLaparoscopyLength of StayMaleMesocolonRetrospective Studies

Identifiers

PMID31440778
OpenAlexW2969536679

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.