ReviewFrontiers in pediatrics2019
Extracorporeal Membrane Oxygenation in Congenital Diaphragmatic Hernia.
Review in Frontiers in pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Effectiveness of prenatal predictors for congenital diaphragmatic hernia on survival to discharge and extracorporeal membrane oxygenation requirement: a retrospective cohort study.Pediatric surgery international · 2026Article
- Repeated Treatments With Extracorporeal Membrane Oxygenation in Congenital Diaphragmatic Hernia Patients: A Registry Analysis.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2026Article
- Measurements of Lung Size in Ultrasound and Magnetic Resonance Imaging in Congenital Diaphragmatic Hernia - A Comparison of Prenatal Imaging Techniques.Ultraschall in der Medizin (Stuttgart, Germany : 1980) · 2025Article
- Growth challenges and recovery in 1247 children with congenital diaphragmatic hernia: a 10-year follow-up.European journal of pediatrics · 2025Article
- Combined extracorporeal membrane oxygenation support and patent ductus arteriosus ligation following surgical correction for congenital diaphragmatic hernia, a case report and literature review.Respiratory medicine case reports · 2025Article
- Risk factors, incidence, and outcomes of neonatal respiratory extracorporeal membrane oxygenation including association with therapeutic hypothermia in California during 2013-2020.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Adoption, Outcomes, and Healthcare Professionals' Perceptions of Minimally Invasive Surgical Techniques in Neonatology and Pediatric Surgery: A Clinical Study.Journal of pharmacy & bioallied sciences · 2024Article
- The role of extracorporeal life support and timing of repair in infants with congenital diaphragmatic hernia.World journal of pediatric surgery · 2024Review
- Editorial: Unsolved problems in congenital diaphragmatic hernia.Frontiers in pediatrics · 2023Article
- Early vasopressin infusion improves oxygenation in infants with congenital diaphragmatic hernia.Frontiers in pediatrics · 2023Article
- Successful extracorporeal membrane oxygenation for postoperative cardiopulmonary failure in newborns with congenital diaphragmatic hernia: case reports and literature reviews.Frontiers in pediatrics · 2023Article
- Impact of Time Point of Extracorporeal Membrane Oxygenation on Mortality and Morbidity in Congenital Diaphragmatic Hernia: A Single-Center Case Series.Children (Basel, Switzerland) · 2022Article
- Congenital diaphragmatic hernia.Nature reviews. Disease primers · 2022Review
- Mediastinal Shift Angle in Fetal MRI Is Associated With Prognosis, Severity, and Cardiac Underdevelopment in Left Congenital Diaphragmatic Hernia.Frontiers in pediatrics · 2022Article
- The heart in congenital diaphragmatic hernia: Knowns, unknowns, and future priorities.Frontiers in pediatrics · 2022Review
- Genetically Modified Mouse Models of Congenital Diaphragmatic Hernia: Opportunities and Limitations for Studying Altered Lung Development.Frontiers in pediatrics · 2022Review
- Outcomes after Extracorporeal Membrane Oxygenation in Neonates with Congenital Diaphragmatic Hernia: A Single-Center Experience.Journal of chest surgery · 2021Article
- Neonatal extra corporeal membrane oxygenation.Indian journal of thoracic and cardiovascular surgery · 2021Article
- Neonatal respiratory and cardiac ECMO in Europe.European journal of pediatrics · 2021Review
- External validation of the Pediatric Extracorporeal Membrane Oxygenation Prediction model for risk adjusting mortality.Perfusion · 2021Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Congenital diaphragmatic hernia (CDH) is characterized by failure of diaphragmatic development with lung hypoplasia and persistent pulmonary hypertension of the newborn (PPHN). If conventional treatment with gentle ventilation and optimized vasoactive medication fails, extracorporeal membrane oxygenation (ECMO) may be considered. The benefits of ECMO in CDH are still controversial, since there are only few randomized trials demonstrating the advantages of this therapeutic option. At present, there is no precise prenatal and/or early postnatal prognostication parameter to predict reversibility of PPHN in CDH patients. Indications for initiating ECMO include either respiratory or circulatory parameters, which are also undergoing continuous refinement. Centers with higher case numbers and the availability of ECMO published promising survival rates, but data on long-term results, including morbidity and quality of life, are rare. Survival might be influenced by the timing of ECMO initiation and the timing of surgical repair. In this regard a trend toward early initiation of ECMO and early surgery on ECMO exists. The results concerning the cannulation modes are similar and a consensus on time limit for ECMO runs does not exist. The use of ECMO in CDH will continue to be evaluated, and prospective randomized trials and registry network are necessary to help answering the addressed questions of patient selection and management.
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Registered trials
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