Evidence map›Paper›PMID 31440445›Full record

ArticleJournal of bone oncology2019

Incidence of fractures in young women with breast cancer - a retrospective cohort study.

Ulla Stumpf, Karel Kostev, Jannis Kyvernitakis, Wolfgang Böcker, Peyman Hadji

Open access · goldAbstract read
In one paragraph

Article in Journal of bone oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  6. Non-metastatic breast cancer patients discontinuing aromatase inhibitor on denosumab: what next?Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Review
  7. Article
  8. Differential fracture risk in breast cancer patients based on endocrine therapy and age: a nationwide cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  9. Review
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  11. Cancer treatment-induced bone loss.The Korean journal of internal medicine · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ulla StumpfDepartment of General, Trauma and Reconstructive Surgery, Munich University Hospital LMU, Munich, Germany.
Karel KostevEpidemiology, IQVIA, Main Airport Center, Unterschweinstiege 2-14, Frankfurt am Main 60549, Germany.
Jannis KyvernitakisBürgerhospital Frankfurt, Frauenklinik - Zentrum für Ultraschalldiagnostik und Pränatalmedizin and Philipps-University of Marburg, Germany.
Wolfgang BöckerDepartment of General, Trauma and Reconstructive Surgery, Munich University Hospital LMU, Munich, Germany.
Peyman HadjiFrankfurt Centre of Bone Health and Philips-University of Marburg, Germany.
Ludwig-Maximilians-Universität München · DEOlgahospital · DEPhilips (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, cancer treatment-induced bone loss (CTIBL) and increased risk of fracture has become an emerging problem as breast cancer (BC) survival has increased due to early diagnosis and improved treatments. In premenopausal women with BC, chemotherapy and tamoxifen are the treatments of choice in hormone receptor-negative and hormone receptor-positive BC respectively. Their effect on fracture risk has only been investigated in a few small-scale studies. Therefore, we investigated the fracture risk in a cohort study based on data from the Disease Analyzer database (IQVIA) and included 1761 individuals with BC and 1761 healthy women for comparison. After applying similar inclusion criteria, patients with BC were matched 1:1 to those without BC with regard to age, index year, and physician. Within 10 years of the index date, 6.4% of healthy women and 14.2% with BC sustained a fracture (log-rank

Indexed as

Breast cancerChemotherapyFractureOsteoporosisPremenopausal womenTamoxifen

Identifiers

PMID31440445
PMCPMC6698802
OpenAlexW2964741583

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.