Evidence map›Paper›PMID 31440303›Full record

ArticleNutrition & metabolism2019

Acute testosterone administration does not affect muscle anabolism.

David D Church, Stefan M Pasiakos, Robert R Wolfe, Arny A Ferrando

Abstract read
In one paragraph

Article in Nutrition & metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Sex-Steroid Signaling in Lung Diseases and Inflammation.Advances in experimental medicine and biology · 2021
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

David D Church1Department of Geriatrics, Donald W. Reynolds Institute on Aging, Center for Translational Research in Aging & Longevity, University of Arkansas for Medical Sciences, Little Rock, AR 72205 USA.
Stefan M Pasiakos2Military Nutrition Division, U.S. Army Research Institute of Environmental Medicine, Natick, MA USA.
Robert R Wolfe1Department of Geriatrics, Donald W. Reynolds Institute on Aging, Center for Translational Research in Aging & Longevity, University of Arkansas for Medical Sciences, Little Rock, AR 72205 USA.
Arny A Ferrando1Department of Geriatrics, Donald W. Reynolds Institute on Aging, Center for Translational Research in Aging & Longevity, University of Arkansas for Medical Sciences, Little Rock, AR 72205 USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously demonstrated that improved net muscle protein balance, via enhanced protein synthetic efficiency, occurs 5 days after testosterone (T) administration. Whether the effects of T on muscle protein kinetics occur immediately upon exposure is not known. We investigated the effects of acute T exposure on leg muscle protein kinetics and selected amino acid (AA) transport using the arteriovenous balance model, and direct calculations of mixed-muscle protein fractional synthesis (FSR) and breakdown (FBR) rates. Four healthy men were studied over a 5 h period with and without T (infusion rate, 0.25 mg·min

Indexed as

Amino acids kineticsProtein breakdownProtein metabolismProtein synthesisStable isotope tracersTestosterone

Identifiers

PMID31440303
PMCPMC6704643

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.