Evidence map›Paper›PMID 31440065›Full record

ArticleInfection and drug resistance2019

Molecular characterization of para-aminosalicylic acid resistant

Ming Luo, Kun Li, Huizheng Zhang, Xiaofeng Yan, Jing Gu, Zhen Zhang, Yu Chen, Jungang Li, Jing Wang, Yaokai Chen

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Rapid drug resistance prediction in positiveEmerging microbes & infections · 2026
    Article
  2. Article
  3. Review
  4. The T120P or M172V mutation onEmerging microbes & infections · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Competition between HAntibiotics (Basel, Switzerland) · 2023
    Article
  9. Association between mutations in aEmerging microbes & infections · 2023
    Article
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ming LuoCentral Laboratory, Chongqing Public Health Medical Center, Chongqing 400036, People's Republic of China.
Kun LiCentral Laboratory, Chongqing Public Health Medical Center, Chongqing 400036, People's Republic of China.
Huizheng ZhangCentral Laboratory, Chongqing Public Health Medical Center, Chongqing 400036, People's Republic of China.
Xiaofeng YanDepartment of Tuberculosis, Chongqing Public Health Medical Center, Chongqing 400036, People's Republic of China.
Jing GuKey Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, People's Republic of China.
Zhen ZhangDepartment of Pharmacy, Chongqing Public Health Medical Center, Chongqing 400036, People's Republic of China.
Yu ChenDepartment of Medical Records, Chongqing Public Health Medical Center, Chongqing 400036, People's Republic of China.
Jungang LiCentral Laboratory, Chongqing Public Health Medical Center, Chongqing 400036, People's Republic of China.
Jing WangCentral Laboratory, Chongqing Public Health Medical Center, Chongqing 400036, People's Republic of China.
Yaokai ChenCentral Laboratory, Chongqing Public Health Medical Center, Chongqing 400036, People's Republic of China.
Chongqing Public Health Medical Center · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study is to investigate para-aminosalicylic acid (PAS) resistance-related gene mutations in clinical PATIENTS AND

methodsTotal 122 PAS-resistant and 55 PAS-susceptible clinical isolates were obtained from Chongqing Public Health Medical Center between April 2014 and January 2018. Drug susceptibility test was performed, and the PAS resistance-related genes were sequenced.

resultsPAS-resistant strains were more likely to resist streptomycin (OR: 9.5, 95% CI: 3.87-23.3;

conclusionPAS drug resistance in MTB in southwestern China is mainly caused by mutations in

Indexed as

molecular characteristicMycobacterium tuberculosispara-aminosalicylic acidresistancesouthwestern China

Identifiers

PMID31440065
PMCPMC6664864
OpenAlexW2964328496

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.