ArticleScience (New York, N.Y.)2019
NAD
Open access · greenAbstract read
In one paragraph
Article in Science (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 239 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
239citing papers in PubMed, 1 pooled it
50.0field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
239 citing papers in PubMed, 1 synthesis or guideline pooled it, 503 citations in OpenAlex.
- Conventional and new-breeding technologies for improving disease resistance in lentil (Frontiers in plant science · 2022Pooled it
- Mechanisms and balanced regulation of plant immunity.Nature reviews. Molecular cell biology · 2026Review
- Domain compositions of Arabidopsis Toll/Interleukin-1 Receptor/Resistance domain-containing TX14 proteins affect localization and induction of the hypersensitive response.Journal of experimental botany · 2026Article
- Review
- Preclinical Pharmacokinetic and Pharmacological Profiling of B339, a Novel SARM1 Inhibitor for the Treatment of Vincristine-induced Peripheral Neuropathy.Pharmaceutical research · 2026Article
- Direct activation of SARM1 by dsDNA is not supported by biochemical and cellular evidence.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- The insect effector CSPs activate an atypical plant TNL immune receptor.Plant cell reports · 2026Article
- Review
- Article
- An atypical EF-hand domain containing resistance protein SRC4 boosts plant immunity in a calcium-enhanced manner.The Plant journal : for cell and molecular biology · 2026Article
- Peripheral Neuropathy in Metabolic Stress.International journal of molecular sciences · 2026Review
- Boldine inhibits SARM1 NADase Activity and Preserves Axonal Integrity After Nerve Injury.bioRxiv : the preprint server for biology · 2026Article
- CabioRxiv : the preprint server for biology · 2026Article
- Transition metal-enhanced immunity in Arabidopsis roots via an NLR pair.Nature plants · 2026Article
- The rise and fall of SARM1 base-exchange inhibitors.Communications chemistry · 2026Article
- Chemical inactivation of a bacterial immune system de-domesticates a temperate phage and promotes its spread.bioRxiv : the preprint server for biology · 2026Article
- TIR-like NADases act in bacterial immunity and the RNA vault.bioRxiv : the preprint server for biology · 2026Article
- Cloning and functional analysis of qCmr2.1, a novel gene for Cucumber mosaic virus resistance in Capsicum frutescens.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Plant NLRs are getting into higher-order architectures.The Plant journal : for cell and molecular biology · 2026Review
- Unraveling plant immunity: from pathogen perception to resistance engineering.Science China. Life sciences · 2026Review
179 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on byNAD2019
Authors and funding
27 authors at 9 institutions in 3 countries.
Shane HorsefieldSchool of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0003-0786-3995
Hayden BurdettSchool of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0003-4803-9660
Xiaoxiao ZhangAgriculture and Food, Commonwealth Scientific and Industrial Research Organisation, Canberra, ACT 2601, Australia.ORCID 0000-0002-5417-6963
Mohammad K ManikSchool of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia.
Yun ShiInstitute for Glycomics, Griffith University, Southport, QLD 4222, Australia.ORCID 0000-0003-3365-4679
Jian ChenAgriculture and Food, Commonwealth Scientific and Industrial Research Organisation, Canberra, ACT 2601, Australia.ORCID 0000-0001-8670-6984
Tiancong QiDepartment of Plant and Microbial Biology, University of California Berkeley, Berkeley, CA 94720, USA.
Jonathan GilleyJohn van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, ED Adrian Building, Forvie Site, Robinson Way, Cambridge CB2 0PY, UK.
Jhih-Siang LaiSchool of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0001-5677-5890
Maxwell X RankSchool of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0001-6962-9235
Lachlan W CaseySchool of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-4458-0137
Weixi GuSchool of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia.
Daniel J EricssonMacromolecular Crystallography (MX) Beamlines, Australian Synchrotron, Melbourne, VIC 3168, Australia.ORCID 0000-0001-5101-9244
Gabriel FoleySchool of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-0487-2629
Robert O HughesDisarm Therapeutics, 400 Technology Square, Cambridge, MA 02139, USA.
Todd BosanacDisarm Therapeutics, 400 Technology Square, Cambridge, MA 02139, USA.
Mark von ItzsteinInstitute for Glycomics, Griffith University, Southport, QLD 4222, Australia.ORCID 0000-0001-6302-7524
John P RathjenPlant Sciences Division, Research School of Biology, The Australian National University, Canberra ACT 2601, Australia.ORCID 0000-0003-4073-8088
Jeffrey D NansonSchool of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia.
Mikael BodenSchool of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0003-3548-268X
Ian B DryAgriculture and Food, Commonwealth Scientific and Industrial Research Organisation, Urrbrae, SA 5064, Australia.ORCID 0000-0001-8900-4427
Simon J WilliamsPlant Sciences Division, Research School of Biology, The Australian National University, Canberra ACT 2601, Australia.ORCID 0000-0003-4781-6261
Brian J StaskawiczDepartment of Plant and Microbial Biology, University of California Berkeley, Berkeley, CA 94720, USA.ORCID 0000-0002-9711-3962
Michael P ColemanJohn van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, ED Adrian Building, Forvie Site, Robinson Way, Cambridge CB2 0PY, UK.
Thomas VeSchool of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia. b.kobe@uq.edu.au t.ve@griffith.edu.au peter.dodds@csiro.au.ORCID 0000-0002-0113-1905
Peter N DoddsAgriculture and Food, Commonwealth Scientific and Industrial Research Organisation, Canberra, ACT 2601, Australia. b.kobe@uq.edu.au t.ve@griffith.edu.au peter.dodds@csiro.au.ORCID 0000-0003-0620-5923
Bostjan KobeSchool of Chemistry and Molecular Biosciences, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia. b.kobe@uq.edu.au t.ve@griffith.edu.au peter.dodds@csiro.au.ORCID 0000-0001-9413-9166
The University of Queensland · AUAustralian National University · AUGriffith University · AUBabraham Institute · GBModerna Therapeutics (United States) · USUniversity of California, Berkeley · USAgriculture and Food · AUAustralian Synchrotron · AUCommonwealth Scientific and Industrial Research Organisation · AU
Funding
Australian Research CouncilMedical Research Council MR/N004582/1
Abstract
SARM1 (sterile alpha and TIR motif containing 1) is responsible for depletion of nicotinamide adenine dinucleotide in its oxidized form (NAD
Indexed as
Protein DomainsAnimalsArmadillo Domain ProteinsAxonsBinding SitesCell DeathConserved SequenceCrystallography, X-RayCytoskeletal ProteinsHEK293 CellsHumansMiceNADNAD+ NucleosidaseNADPNeuronsArmadillo Domain ProteinsCytoskeletal ProteinsL6 protein, Linum usitatissimumNADNAD+ NucleosidaseNADPPlant ProteinsReceptors, ImmunologicSARM1 protein, human
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.