Evidence map›Paper›PMID 31439678›Full record

ArticleHaematologica2020

Genomic profiling of primary histiocytic sarcoma reveals two molecular subgroups.

Caoimhe Egan, Alina Nicolae, Justin Lack, Hye-Jung Chung, Shannon Skarshaug, Thu Anh Pham, Winnifred Navarro, Zied Abdullaev, Nadine S Aguilera, Liqiang Xi and 4 more

Open access · goldAbstract read
In one paragraph

Article in Haematologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 92 citations in OpenAlex.

  1. Review
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  12. Histiocytic Sarcoma: A Review and Update.International journal of molecular sciences · 2025
    Review
  13. Article
  14. Article
  15. Recent advances in therapeutic strategies of Erdheim-Chester disease.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
  16. Article
  17. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Caoimhe EganLaboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Alina NicolaeLaboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Justin LackNIAID Collaborative Bioinformatics Resource (NCBR), National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.
Hye-Jung ChungLaboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Shannon SkarshaugLaboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Thu Anh PhamLaboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Winnifred NavarroLaboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Zied AbdullaevLaboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Nadine S AguileraUniversity of Virginia Health System, Charlottesville, VA, USA.
Liqiang XiLaboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Svetlana PackLaboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Stefania PittalugaLaboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Elaine S JaffeLaboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Mark RaffeldLaboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD mraff@mail.nih.gov.
National Institutes of Health · USNational Cancer Institute · USUniversity of Virginia Health System · US

Funding

Lymphoma Disease Discovery and DefintionZIASC000550 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · PI JAFFE, ELAINE · 2009 to 2025
$16.9M
Development of FISH Molecular Diagnostics to support Clinical Trials at NCIZIDBC011792 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI XI, LIQIANG · 2017 to 2024
$4.5M
Molecular Mechanisms of Cancer DevelopmentZICBC011842 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI PACK, SVETLANA · 2018 to 2020
$458k
6 · The paper itself

Abstract

Histiocytic sarcoma is a rare malignant neoplasm that may occur

Indexed as

Histiocytic SarcomaGenomicsHomozygoteHumansMutationSequence Deletion

Identifiers

PMID31439678
PMCPMC7109753
OpenAlexW2969481187

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.