Evidence map›Paper›PMID 31439668›Full record

ArticleThe Journal of biological chemistry2019

C1q/TNF-related protein 2 (CTRP2) deletion promotes adipose tissue lipolysis and hepatic triglyceride secretion.

Xia Lei, G William Wong

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
  2. Article
  3. CTRP10 is required for optimal motor function.The Journal of biological chemistry · 2026
    Article
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  14. Review
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  16. Review
  17. CTRP14 inactivation alters physical activity and food intake response to fasting and refeeding.American journal of physiology. Endocrinology and metabolism · 2022
    Article
  18. CTRP11 contributes modestly to systemic metabolism and energy balance.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Xia LeiDepartment of Physiology and Center for Metabolism and Obesity Research, School of Medicine, The Johns Hopkins University, Baltimore, Maryland 21205 xia.lei@okstate.edu.ORCID 0000-0003-4241-6576
G William WongDepartment of Physiology and Center for Metabolism and Obesity Research, School of Medicine, The Johns Hopkins University, Baltimore, Maryland 21205 gwwong@jhmi.edu.
Johns Hopkins University · US

Funding

CTRP and Metabolic ControlR01DK084171 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI Guang William Wong · 2010 to 2026
$8.0M
NIDDK NIH HHS R01 DK084171
6 · The paper itself

Abstract

The highly conserved C1q/TNF-related protein (CTRP) family of secreted hormones has emerged as important regulators of insulin action and of sugar and fat metabolisms. Among these, the specific biological function of CTRP2 remains elusive. Here, we show that the expression of human

Indexed as

Gene DeletionLipolysis3T3-L1 CellsAdipose TissueAdiposityAnimalsBody WeightCholesterolComplement System ProteinsDiet, High-FatEnergy MetabolismHumansIntercellular Signaling Peptides and ProteinsLiverMaleMiceC1QTNF2 protein, humanCholesterolComplement System ProteinsCTRP2 protein, mouseIntercellular Signaling Peptides and ProteinsTriglyceridesadipocyte biologyadipokineadipose tissueC1q familyC1q/TNF-related proteinCTRPdyslipidemiaendocrine metabolismhepatic triglyceride secretionlipid metabolismlipolysisliver metabolismobesitysecreted protein

Identifiers

PMID31439668
PMCPMC6816104
OpenAlexW2969783788

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.