ArticleEuropean journal of radiology2019
MRI in differentiating malignant versus benign portal vein thrombosis in patients with hepatocellular carcinoma: Value of post contrast imaging with subtraction.
Article in European journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Dual-layer spectral detector computed tomography in distinguishing between bland and neoplastic portal vein thrombosis.Quantitative imaging in medicine and surgery · 2025Article
- Value of dual-energy computed tomography quantitative parameters in differentiating neoplastic from bland portal vein thrombosis.Quantitative imaging in medicine and surgery · 2025Article
- Development of a Novel Comprehensive Hepatocellular Carcinoma Outcome Prognostic Scoring System With Integration of Imaging Features.The oncologist · 2024Article
- Role of contrast-enhanced ultrasound for differentiation of benign vs. malignant portal vein thrombosis in hepatocellular carcinoma - A systematic review a meta-analysis.Australasian journal of ultrasound in medicine · 2024Article
- Value of susceptibility-weighted imaging in differentiating benign from malignant portal vein thrombosis.Quantitative imaging in medicine and surgery · 2023Article
- MRI diffusion-weighted imaging detects a fresh portal vein thrombus as a high intensity lesion in a patient with a liver transplant: A case report.Acta radiologica open · 2021Article
- LI-RADS and transplantation: challenges and controversies.Abdominal radiology (New York) · 2021Review
- Portal Vein Thrombosis in Cirrhosis.Journal of clinical and experimental hepatologyReview
- The ABCD of portal vein thrombosis: a systematic approach.Radiologia brasileiraArticle
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7 authors.
Funding
Abstract
purposeTo evaluate MR imaging parameters including quantitative multiphasic post-contrast enhancement with subtraction and qualitative diffusion weighted imaging (DWI) in differentiating benign versus malignant portal venous thrombosis (PVT) in patients with hepatocellular carcinoma (HCC).
methodRadiology reports over a 6-year period ending February 2016 were searched for key words indicating presence of both HCC and PVT on abdominal MRI. 39 patients were identified with PVT characterized as benign or malignant based on pathologic data or serial imaging growth criteria. Image review was performed by two subspecialized radiologists blinded to the diagnosis and medical chart. Signal intensity for regions of interest were recorded within the portal vein thrombus as well as the portal vein on pre-contrast and dynamic post-contrast phases without and with subtraction. Qualitative parameters for DWI and presence of PV expansion were also evaluated.
resultsPercent enhancement generated high area under the curve (AUC) for both readers on all non-subtraction phases: arterial (0.95/0.98), portal venous (0.97/0.97) and delayed phase (0.96/0.99) and subtraction phases: arterial (0.91/0.96), portal venous (0.94/0.99) and delayed phases (0.96/0.97). Statistically significant differences were observed between benign and malignant PVT for both readers for PV expansion (p= <0.001/0.006). No qualitative DWI parameter reached statistical significance for both readers.
conclusionsPost-contrast and subtraction MRI can reliably distinguish malignant from benign PVT in patients with HCC using subtracted or non-subtracted images and at arterial, portal venous, or delayed phase timing.
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