Evidence map›Paper›PMID 31438871›Full record

ArticleBMC nephrology2019

An evaluation of phase angle, bioelectrical impedance vector analysis and impedance ratio for the assessment of disease status in children with nephrotic syndrome.

Steven Brantlov, Lars Jødal, René Frydensbjerg Andersen, Aksel Lange, Søren Rittig, Leigh C Ward

Abstract read
In one paragraph

Article in BMC nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. Review
  10. Bioimpedance basics and phase angle fundamentals.Reviews in endocrine & metabolic disorders · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Steven BrantlovDepartment of Procurement and Clinical Engineering, Aarhus University Hospital, Central Denmark Region, Olof Palmes Allé 15, 8200, Aarhus, Denmark. stebra@rm.dk.ORCID 0000-0001-6324-9215
Lars JødalDepartment of Nuclear Medicine, Aalborg University Hospital, Aalborg, Denmark.ORCID 0000-0002-6811-0172
René Frydensbjerg AndersenDepartment of Paediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0001-8045-7147
Aksel LangeDepartment of Paediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0003-2782-4475
Søren RittigDepartment of Paediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0001-7038-1652
Leigh C WardSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia.ORCID 0000-0003-2378-279X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOedema, characterized by accumulation of extracellular water (ECW), is one of the major clinical manifestations in children suffering from nephrotic syndrome (NS). The lack of a simple, inexpensive and harmless method for assessing ECW may be solved by the use of the bioelectrical impedance analysis (BIA) technique. The aims of this study were to examine whether phase angle (PA), bioelectrical impedance vector analysis (BIVA) and the impedance ratio (IR) reflect change in disease status in children with NS.

methodsEight children (age range: 2-10 years) with active NS (ANS group) were enrolled. In five of these (ANS* subgroup), impedance was also measured at remission (NSR group). Thirty-eight healthy children (age range: 2-10 years) were included as healthy controls (HC group). Whole-body impedance was measured with a bioimpedance spectroscopy device (Xitron 4200) with surface electrodes placed on the wrist and ankle.

resultsValues of PA, BIVA and IR were found to be significantly lower (p-value range < 0.001 to < 0.01) in the ANS patients compared to the HC and NSR groups. No significant differences were observed between the NSR and HC groups.

conclusionThe studied parameters can be used to assess change in disease status in NS patients. Data were consistent with NS being associated with expansion of ECW.

Indexed as

Body WaterElectric ImpedanceCase-Control StudiesChildChild, PreschoolDielectric SpectroscopyEdemaFemaleHumansMaleNephrotic SyndromeBioelectrical impedance vector analysisChildrenElectrical impedanceImpedance ratioNephrotic syndromePhase angleTotal body water

Identifiers

PMID31438871
PMCPMC6704501

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.