Evidence map›Paper›PMID 31438854›Full record

ArticleBMC genomics2019

Genome-wide identification of histone methylation (H3K9

Vasudevan Ayyappan, Venkateswara R Sripathi, Venu Kal Kalavacharla, Malay C Saha, Jyothi Thimmapuram, Ketaki P Bhide, Elizabeth Fiedler

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC genomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Vasudevan AyyappanMolecular Genetics and Epigenomics Laboratory, College of Agriculture and Related Sciences, Delaware State University, Dover, DE, USA.
Venkateswara R SripathiMolecular Biology and Bioinformatics Laboratory, College of Agricultural, Life and Natural Sciences, Alabama A&M University, Normal, AL, USA.
Venu Kal KalavacharlaMolecular Genetics and Epigenomics Laboratory, College of Agriculture and Related Sciences, Delaware State University, Dover, DE, USA. vkalavacharla@desu.edu.
Malay C SahaNoble Research Institute, Ardmore, OK, USA.
Jyothi ThimmapuramBioinformatics Core, Purdue University, West Lafayette, IN, USA.
Ketaki P BhideBioinformatics Core, Purdue University, West Lafayette, IN, USA.
Elizabeth FiedlerMolecular Genetics and Epigenomics Laboratory, College of Agriculture and Related Sciences, Delaware State University, Dover, DE, USA.
Delaware State University · USPurdue University West Lafayette · USAlabama Agricultural and Mechanical University · USNoble Research Institute · US

Funding

National Science Foundation EPS-0814251
6 · The paper itself

Abstract

backgroundHistone modifications play a significant role in the regulation of transcription and various biological processes, such as development and regeneration. Though a few genomic (including DNA methylation patterns) and transcriptomic studies are currently available in switchgrass, the genome-wide distribution of histone modifications has not yet been studied to help elucidate gene regulation and its application to switchgrass improvement.

resultsThis study provides a comprehensive epigenomic analyses of two contrasting switchgrass ecotypes, lowland (AP13) and upland (VS16), by employing chromatin immunoprecipitation sequencing (ChIP-Seq) with two histone marks (suppressive- H3K9

conclusionsThe genome-wide histone modifications reported here can be utilized in understanding the regulation of genes important in the phenylpropanoid-monolignol biosynthesis pathway, which in turn, may help understand the recalcitrance associated with conversion of biomass to biofuel, a major roadblock in utilizing lignocellulosic feedstocks.

Indexed as

GenomicsAcetylationCell RespirationEpigenomicsGenome, PlantHistonesLysineMethylationPanicumPhotosynthesisTranscription FactorsHistonesLysineTranscription FactorsAnd monolignolsChIP-SeqDifferential bindingEpigenomeHistone modificationsPhenylpropanoid pathwaySwitchgrass

Identifiers

PMID31438854
PMCPMC6704705
OpenAlexW2969415512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.