ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2019
Where did the pupa come from? The timing of juvenile hormone signalling supports homology between stages of hemimetabolous and holometabolous insects.
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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36 citing papers in PubMed, 95 citations in OpenAlex.
- Paracetamol Responses Depend on Temperature, Life Stage, and Genetic Background inMedicines (Basel, Switzerland) · 2026Article
- Two cytochrome P450 epoxidases mediate juvenile hormone biosynthesis in Drosophila melanogaster.Insect biochemistry and molecular biology · 2026Article
- Evolution of complete metamorphosis through temporal shifts in Chronologically inappropriate morphogenesis (Chinmo) and Broad.Development (Cambridge, England) · 2026Article
- Two cytochrome P450 epoxidases mediate juvenile hormone biosynthesis inbioRxiv : the preprint server for biology · 2025Article
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- The Dangers of Growing Old: Adult Moths Face Higher Predation Pressures than Caterpillars inInsects · 2025Article
- Krüppel homolog 1, a juvenile hormone transcription factor, regulates the reproduction and development of Aedes albopictus(Skuse) (Diptera: Culicidae).Parasitology research · 2025Article
- Developmental Expression Patterns of miRNA inGenes · 2025Article
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- Developmental correspondence of juvenile stages across the locust, harlequin ladybird, and diamondback moth.iScience · 2024Article
- Juvenile hormone signaling is indispensable for late embryogenesis in ametabolous and hemimetabolous insects.BMC biology · 2024Article
- Rapid growth and the evolution of complete metamorphosis in insects.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
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- Anatomical changes of Tenebrio molitor and Tribolium castaneum during complete metamorphosis.Cell and tissue research · 2024Article
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- Pri peptides temporally coordinate transcriptional programs during epidermal differentiation.Science advances · 2024Article
- The embryonic role of juvenile hormone in the firebrat,bioRxiv : the preprint server for biology · 2024Article
- The Juvenile-Hormone-Responsive FactorBiomolecules · 2023Article
- A transcription factor that enables metamorphosis.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Article
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1 author at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Insect metamorphosis boasts spectacular cases of postembryonic development when juveniles undergo massive morphogenesis before attaining the adult form and function; in moths or flies the larvae do not even remotely resemble their adult parents. A selective advantage of complete metamorphosis (holometaboly) is that within one species the two forms with different lifestyles can exploit diverse habitats. It was the environmental adaptation and specialization of larvae, primarily the delay and internalization of wing development, that eventually required an intermediate stage that we call a pupa. It is a long-held and parsimonious hypothesis that the holometabolous pupa evolved through modification of a final juvenile stage of an ancestor developing through incomplete metamorphosis (hemimetaboly). Alternative hypotheses see the pupa as an equivalent of all hemimetabolous moulting cycles (instars) collapsed into one, and consider any preceding holometabolous larval instars free-living embryos stalled in development. Discoveries on juvenile hormone signalling that controls metamorphosis grant new support to the former hypothesis deriving the pupa from a final pre-adult stage. The timing of expression of genes that repress and promote adult development downstream of hormonal signals supports homology between postembryonic stages of hemimetabolous and holometabolous insects. This article is part of the theme issue 'The evolution of complete metamorphosis'.
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