Evidence map›Paper›PMID 31438528›Full record

ArticleMarine drugs2019

Indole-4-carboxaldehyde Isolated from Seaweed,

Seon-Heui Cha, Yongha Hwang, Soo-Jin Heo, Hee-Sook Jun

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Antibacterial Activity and Mechanism ofInternational journal of molecular sciences · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Seon-Heui ChaDepartment of Marine Biomedical Sciences, Hanseo University, Chungcheongnam-do 31962, Korea.ORCID 0000-0002-5004-3223
Yongha HwangLee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon 21999, Korea.
Soo-Jin HeoJeju International Marine Science Center for Research & Education, Korea Institute of Ocean Science & Technology (KIOST), Jeju 63349, Korea.
Hee-Sook JunLee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon 21999, Korea. hsjun@gachon.ac.kr.ORCID 0000-0002-1166-4932
Gachon University · KRHanseo University · KRKorea Institute of Ocean Science and Technology · KR

Funding

Ministry of Health and Welfare of Korea HI14C1135
6 · The paper itself

Abstract

Glucose degradation is aberrantly increased in hyperglycemia, which causes various harmful effects on the liver. Glyoxalase-1 (Glo-1) is a ubiquitous cellular enzyme that participates in the detoxification of methylglyoxal (MGO), a cytotoxic byproduct of glycolysis that induces protein modification (advanced glycation end-products, AGEs) and inflammation. Here, we investigated the anti-inflammatory effect of indole-4-carboxaldehyde (ST-I4C), which was isolated from the edible seaweed

Indexed as

Anti-Inflammatory AgentsDrug Evaluation, PreclinicalGlycation End Products, AdvancedGlycolysisHep G2 CellsHumansIndolesLactoylglutathione LyaseNF-kappa BNon-alcoholic Fatty Liver DiseasePyruvaldehydeReceptor for Advanced Glycation End ProductsSargassumSeaweedSignal TransductionAGER protein, humanAnti-Inflammatory AgentsGLO1 protein, humanGlycation End Products, AdvancedIndolesLactoylglutathione LyaseNF-kappa BPyruvaldehydeReceptor for Advanced Glycation End ProductsAGEshepatic steatosismetabolic diseaseSargassum thunbergiiseaweed

Identifiers

PMID31438528
PMCPMC6780312
OpenAlexW2969780520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.