Evidence map›Paper›PMID 31437911›Full record

ArticleStudies in health technology and informatics2019

Pretraining to Recognize PICO Elements from Randomized Controlled Trial Literature.

Tian Kang, Shirui Zou, Chunhua Weng

Abstract read
In one paragraph

Article in Studies in health technology and informatics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. A span-based model for extracting overlapping PICO entities from randomized controlled trial publications.Journal of the American Medical Informatics Association : JAMIA · 2024
    Trial
  5. EvidenceMap: a three-level knowledge representation for medical evidence computation and comprehension.Journal of the American Medical Informatics Association : JAMIA · 2023
    Trial
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. PICOT questions and search strategies formulation: A novel approach using artificial intelligence automation.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. A Scoping Review of Adopted Information Extraction Methods for RCTs.Medical journal of the Islamic Republic of Iran · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tian KangDepartment of Biomedical Informatics, Columbia University, New York, NY, United States.
Shirui ZouLongstar Healthpro, Inc., Los Angeles, CA, United States.
Chunhua WengDepartment of Biomedical Informatics, Columbia University, New York, NY, United States.

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Bridging the Semantic Gap Between Research Eligibility Criteria and Clinical DataR01LM009886 · NLM · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WENG, CHUNHUA · 2009 to 2020
$5.3M
Biomedical Data Translator Technical Feasibility Assessment and Architecture DesignOT3TR002027 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DUMONTIER, MICHEL, TATONETTI, NICHOLAS P · 2016 to 2019
$2.7M
NCATS NIH HHS OT3 TR002027NCATS NIH HHS UL1 TR001873NLM NIH HHS R01 LM009886
6 · The paper itself

Abstract

PICO (Population/problem, Intervention, Comparison, and Outcome) is widely adopted for formulating clinical questions to retrieve evidence from the literature. It plays a crucial role in Evidence-Based Medicine (EBM). This paper contributes a scalable deep learning method to extract PICO statements from RCT articles. It was trained on a small set of richly annotated PubMed abstracts using an LSTM-CRF model. By initializing our model with pretrained parameters from a large related corpus, we improved the model performance significantly with a minimal feature set. Our method has advantages in minimizing the need for laborious feature handcrafting and in avoiding the need for large shared annotated data by reusing related corpora in pretraining with a deep neural network.

Indexed as

Evidence-Based MedicineNeural Networks, ComputerPubMedRandomized Controlled Trials as TopicEvidence-Based MedicineNatural Language ProcessingRandomized Controlled Trial

Identifiers

PMID31437911
PMCPMC6852618

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.