ReviewRespiratory medicine2019
Spirometric indices of early airflow impairment in individuals at risk of developing COPD: Spirometry beyond FEV
Review in Respiratory medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.
- Spirometry parameters used to define small airways obstruction in population-based studies: systematic review.Respiratory research · 2022Pooled it
- The effect of smoking on lung function changes during a 16-week combined exercise program in middle-aged workers: a latent growth curve analysis.European journal of applied physiology · 2025Trial
- A bibliometric analysis of quantitative computed tomography in chronic obstructive pulmonary disease research based on Web of Science: trends, hotspots, and future directions (2005-2025).Journal of thoracic disease · 2026Article
- Early dysanapsis in experimental bronchopulmonary dysplasia: implications for lifelong lung disease.American journal of physiology. Lung cellular and molecular physiology · 2026Article
- Current use and future potential of oscillometry in UK lung function testing: a national survey.BMJ open respiratory research · 2026Article
- Clinical Significance of Reduced Forced Expiratory Volume in 3 Seconds to Forced Expiratory Volume in 6 Seconds in Adults.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2026Article
- Circulating extracellular microRNAs as tissue-specific biomarkers of human health and disease.Nature communications · 2026Article
- Chronic Obstructive Pulmonary Disease and Asthma Among Workers and Residents of Navanakorn Industrial Zone, Thailand.Medical sciences (Basel, Switzerland) · 2026Article
- Small Airway Dysfunction in Chronic Obstructive Pulmonary Disease Pathology: Assessment and Clinical Implications.Tuberculosis and respiratory diseases · 2026Article
- Prolonged expiratory time constant and risk of moderate-to-severe exacerbations in stable COPD.Scientific reports · 2026Article
- Prevalence of Reduced Mid-Expiratory Flow Among Coal Workers' Health Surveillance Program Participants.American journal of industrial medicine · 2025Article
- Expected health risk out of black carbon and particulate matter in the indoor environment of an industrial cluster of chandigarh in India.Scientific reports · 2025Article
- Spirometry update 2019: phase 4 forced maximal inspiration and new acceptability criteria.Breathe (Sheffield, England) · 2025Article
- Labor Status at Delivery and Lung Function in Extremely Prematurely Born Young Adults.Pediatric pulmonology · 2025Article
- A Bibliometric Analysis of Pulmonary Function Testing in Differentiating Asthma From COPD: Trends, Impact, and Emerging Research Areas.Journal of multidisciplinary healthcare · 2025Review
- Reduced FEVInternational journal of chronic obstructive pulmonary disease · 2025Article
- Quantitative Characterization of Respiratory Patterns on Dynamic Higher Temporal Resolution MRI to Stratify Postacute Covid-19 Patients by Cardiopulmonary Symptom Burden.Journal of magnetic resonance imaging : JMRI · 2024Article
- Machine learning approach to flare-up detection and clustering in chronic obstructive pulmonary disease (COPD) patients.Health information science and systems · 2024Article
- Impact of different intravenous bolus rates on fluid and electrolyte balance and mortality in critically ill patients.World journal of critical care medicine · 2024Review
- Proteomic networks and related genetic variants associated with smoking and chronic obstructive pulmonary disease.BMC genomics · 2024Article
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
Spirometry is the current gold standard for diagnosing and monitoring the progression of Chronic Obstructive Pulmonary Disease (COPD). However, many current and former smokers who do not meet established spirometric criteria for the diagnosis of this disease have symptoms and clinical courses similar to those with diagnosed COPD. Large longitudinal observational studies following individuals at risk of developing COPD offer us additional insight into spirometric patterns of disease development and progression. Analysis of forced expiratory maneuver changes over time may allow us to better understand early changes predictive of progressive disease. This review discusses the theoretical ability of spirometry to capture fine pathophysiologic changes in early airway disease, highlights the shortcomings of current diagnostic criteria, and reviews existing evidence for spirometric measures which may be used to better detect early airflow impairment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.