SynthesisJornal de pediatria
Risk factors associated with the outcomes of pediatric bacterial meningitis: a systematic review.
Synthesis in Jornal de pediatria. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Long-Term Outcomes Following Bacterial Meningitis in Childhood: A Systematic Review and Meta-Analysis.Journal of paediatrics and child health · 2026Pooled it
- Clinical utility of a cerebrospinal fluid multiplex PCR meningitis/encephalitis panel in children: a retrospective review of positive results.BMC infectious diseases · 2026Article
- Does cerebrospinal fluid multiplex polymerase chain reaction meningitis panel help manage children with meningitis?Research square · 2025Article
- Clinical characteristics and risk factors for imaging abnormalities in pediatric Group B Streptococcus meningitis: a multicenter study.Translational pediatrics · 2025Article
- The Association Between Elevated Estimated Glomerular Filtration Rate and Poor Clinical Outcomes of Pediatric Patients with Community-Acquired Bacterial Meningitis Receiving Vancomycin: A Ten-Year Retrospective Cohort Study.Infectious diseases and therapy · 2025Article
- Treatment outcome and determinant factors of bacterial meningitis at pediatric ward: a multicenter study from Northwest Ethiopia.Scientific reports · 2025Article
- Clinical features and long-term outcomes of children with pneumococcal meningitis in China: a 10-year single-centre retrospective analysis.BMC pediatrics · 2025Article
- Identifying the need for surgical intervention in pediatric bacterial meningitis: single-center experience.Frontiers in pediatrics · 2025Article
- Practice patterns in pediatric infectious encephalopathy in four centers in Africa.Frontiers in pediatrics · 2024Article
- Geography and public health: analysis of the epidemiological dynamics of meningitis in Brazil, between 2010 and 2019.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2024Article
- Article
- High-risk factors associated with refractory childhood bacterial meningitis in Southwest China.BMC pediatrics · 2023Article
- High Concentration of Protein Oxidation Biomarker O-Tyr/Phe Predicts Better Outcome in Childhood Bacterial Meningitis.Antioxidants (Basel, Switzerland) · 2023Article
- Bacterial meningitis in children with an abnormal craniocerebral structure.Frontiers in pediatrics · 2023Article
- Back to School: Academic Functioning and Educational Needs among Youth with Acquired Brain Injury.Children (Basel, Switzerland) · 2022Review
- FilmArray® Meningoencephalitis panel in the diagnosis of central nervous system infections: stewardship and cost analysis in a paediatric hospital in Chile.BMC pediatrics · 2022Observational
- Targeting the BspC-vimentin interaction to develop anti-virulence therapies during Group B streptococcal meningitis.PLoS pathogens · 2022Article
- Treatment outcome and associated factors of bacterial meningitis at pediatric wards of southwestern Ethiopian hospital: a prospective observational study.Journal of pharmaceutical health care and sciences · 2021Article
- Bacterial Meningitis in Children: Neurological Complications, Associated Risk Factors, and Prevention.Microorganisms · 2021Review
- Epidemiological and Financial Aspects of Hospitalizations for Bacterial Meningitis in Brazil.Journal of global infectious diseasesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to systematically review the literature and answer the following central question: "What are the risk factors associated with worse clinical outcomes of pediatric bacterial meningitis patients?"
methodsThe articles were obtained through literary search using electronic bibliographic databases: Web of Science, Scopus, MEDLINE, and LILACS; they were selected using the international guideline outlined by the Preferred Reporting Items for Systematic Reviews and Meta-analysis Protocols.
resultsThe literature search identified 1,244 articles. After methodological screening, 17 studies were eligible for this systematic review. A total of 9,581 patients aged between 0 days and 18 years were evaluated in the included studies, and several plausible and important prognostic factors are proposed for prediction of poor outcomes after bacterial meningitis in childhood. Late diagnosis reduces the chances for a better evolution and reinforces the importance of a high diagnostic suspicion of meningitis, especially in febrile pictures with nonspecific symptomatology. S. pneumoniae as a causative pathogen was demonstrated to be related to clinical severity.
conclusionsEarly prediction of an adverse outcome may help determine which children require more intensive or longer follow-up and may provide the physician with rationale for parental counseling about their child's prognosis in an early phase of the disease.
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Registered trials
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