Evidence map›Paper›PMID 31437399›Full record

ArticleThe journal of physical chemistry. B2019

Computational Studies of Catalytic Loop Dynamics in

Hua Deng, Shan Ke, Robert Callender, Gurusamy Balakrishnan, Thomas G Spiro, Eric R May, Charles L Brooks

Abstract read
In one paragraph

Article in The journal of physical chemistry. B, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Allostery in Protein Tyrosine Phosphatases is Enabled by Divergent Dynamics.Journal of chemical information and modeling · 2024
    Article
  3. Loop Dynamics and Enzyme Catalysis in Protein Tyrosine Phosphatases.Journal of the American Chemical Society · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Hua DengDepartment of Biochemistry , Albert Einstein College of Medicine , 1300 Morris Park Avenue , Bronx , New York 10461 , United States.ORCID 0000-0002-9503-7572
Shan KeDepartment of Biochemistry , Albert Einstein College of Medicine , 1300 Morris Park Avenue , Bronx , New York 10461 , United States.
Robert CallenderDepartment of Biochemistry , Albert Einstein College of Medicine , 1300 Morris Park Avenue , Bronx , New York 10461 , United States.
Gurusamy BalakrishnanDepartment of Chemistry , University of Washington , Seattle , Washington 98195 , United States.
Thomas G SpiroDepartment of Chemistry , University of Washington , Seattle , Washington 98195 , United States.
Eric R MayDepartment of Molecular and Cell Biology , University of Connecticut , 91 N. Eagleville Road , Storrs , Connecticut 06269 , United States.ORCID 0000-0001-8826-1990
Charles L BrooksDepartment of Chemistry and Biophysics Program , University of Michigan , 930 North University Avenue , Ann Arbor , Michigan 48109 , United States.ORCID 0000-0002-8149-5417
Albert Einstein College of Medicine · USUniversity of Washington · USUniversity of Connecticut · USUniversity of Michigan · US

Funding

Proton Transfer Dynamics in Heme-Copper OxidasesP01GM068036 · NIGMS · ALBERT EINSTEIN COL OF MED YESHIVA UNIV · PI CALLENDER, ROBERT · 2004 to 2018
$26.4M
Theory and Modeling of Biomolecules and their Interactions - Equipment SupplementR35GM130587 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHARLES L BROOKS · 2019 to 2026
$6.9M
ULTRAVIOLET RAMAN STUDIES OF PROTEINS AND NUCLEIC ACIDSR01GM025158 · NIGMS · UNIVERSITY OF WASHINGTON · PI SPIRO, THOMAS G. · 1985 to 2014
$5.1M
Structural Dynamics of Viral Proteins: Development and Application of Multiscale Computational Methods for Studying Viral Capsids, Proteins and Membrane SystemsR35GM119762 · NIGMS · UNIVERSITY OF CONNECTICUT STORRS · PI Eric Robert May · 2016 to 2026
$4.1M
Theoretical Studies of Receptor-Ligand InteractionsR01GM037554 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BROOKS, CHARLES L · 1987 to 2018
$3.8M
NIGMS NIH HHS P01 GM068036NIGMS NIH HHS R01 GM025158NIGMS NIH HHS R01 GM037554NIGMS NIH HHS R35 GM119762NIGMS NIH HHS R35 GM130587
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Molecular Dynamics SimulationBiocatalysisProtein ConformationProtein Tyrosine PhosphatasesThermodynamicsYersiniaProtein Tyrosine Phosphatases

Identifiers

PMID31437399
PMCPMC6752976
OpenAlexW2969296733

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.