Evidence map›Paper›PMID 31437243›Full record

ArticlePloS one2019

Perceived barriers to pre-exposure prophylaxis use among HIV-negative men who have sex with men in Tijuana, Mexico: A latent class analysis.

Rudy Patrick, Jennifer Jain, Alicia Harvey-Vera, Shirley J Semple, Gudelia Rangel, Thomas L Patterson, Heather A Pines

Abstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rudy PatrickDepartment of Medicine, University of California San Diego, La Jolla, CA, United States of America.
Jennifer JainDepartment of Medicine, University of California San Diego, La Jolla, CA, United States of America.
Alicia Harvey-VeraDepartment of Medicine, University of California San Diego, La Jolla, CA, United States of America.
Shirley J SempleDepartment of Psychiatry, University of California San Diego, La Jolla, CA, United States of America.
Gudelia RangelUS-Mexico Border Health Commission, Tijuana, Mexico.
Thomas L PattersonDepartment of Psychiatry, University of California San Diego, La Jolla, CA, United States of America.
Heather A PinesDepartment of Medicine, University of California San Diego, La Jolla, CA, United States of America.ORCID 0000-0002-7173-1981

Funding

Training Program in Substance Use, HIV and Related InfectionsT32DA023356 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Natasha Martin, Steffanie A Strathdee · 2007 to 2026
$7.8M
HIV case finding and genetic transmission networks among MSM in Tijuana, MexicoR01DA037811 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PATTERSON, THOMAS L. · 2014 to 2018
$3.2M
Sexual Networks and HIV Transmission Clusters among Substance Using MSMK01DA040543 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PINES, HEATHER ALISA · 2015 to 2019
$901k
NIDA NIH HHS K01 DA040543NIDA NIH HHS R01 DA037811NIDA NIH HHS T32 DA023356
6 · The paper itself

Abstract

backgroundGiven the slow uptake of PrEP among cisgender men who have sex with men (MSM) in high-income countries, efforts to roll-out PrEP in low- and middle-income countries (LMIC) should address barriers to PrEP use to facilitate its more rapid uptake. To inform PrEP programs in LMIC, we examined patterns of perceived barriers to PrEP use among HIV-negative MSM in Tijuana, Mexico.

methodsFrom 03/2016-09/2017, 364 MSM completed interviewer-administered surveys assessing perceived barriers to PrEP use across 4 domains: PrEP attribute, individual, interpersonal, and structural. Latent class analysis was performed to identify distinct classes with respect to perceived barriers to PrEP use. Multinomial logistic regression was used to identify factors associated with class membership.

resultsWe identified three classes characterized by (1) high levels of perceived barriers across domains (12%), (2) low levels of perceived barriers across domains (43%), and (3) perceived PrEP attribute barriers (i.e., side-effects and cost) (45%). Membership in the high level of perceived barriers class (vs. the low level of perceived barriers class) was positively associated with having a history of incarceration (AOR: 2.44; 95% CI: 1.04, 5.73) and negatively associated with more social support (AOR: 0.99; 95% CI: 0.98, 1.00). Membership in the perceived PrEP attribute barriers class was positively associated with having seen a healthcare provider in the past year (AOR: 2.78; 95% CI: 1.41, 5.45) and negatively associated with having any HIV-positive or status unknown partners (AOR: 0.56; 95% CI: 0.31, 1.01).

conclusionsSince most participants were in either the low level of perceived barriers class or the perceived PrEP attribute barriers class, future PrEP uptake may be high among MSM in Tijuana. However, these findings suggest that achieving sufficient PrEP uptake and adherence among MSM in Tijuana may require a range of comprehensive HIV prevention interventions.

Indexed as

Homosexuality, MaleLatent Class AnalysisPre-Exposure ProphylaxisAdultHealth Services AccessibilityHIV InfectionsHumansMaleMexicoRisk Factors

Identifiers

PMID31437243
PMCPMC6705824

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.