ArticlePloS one2019
Knowledge, attitudes and practices regarding antibiotic use in Maputo City, Mozambique.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Drivers of inappropriate use of antibiotics among community members in low- and middle-income countries: a systematic review of qualitative studies.BMC public health · 2025Pooled it
- Prevalence of knowledge, attitudes, and practices regarding antimicrobial resistance in Africa: a systematic review and meta-analysis.Frontiers in microbiology · 2024Pooled it
- Income level and antibiotic misuse: a systematic review and dose-response meta-analysis.The European journal of health economics : HEPAC : health economics in prevention and care · 2022Pooled it
- Analysis on the Prevalence and Practices of Antibiotic Misuse among Adult Residents of Rodriguez, Rizal: An Explanatory Sequential Mixed Methods Study.Acta medica Philippina · 2026Article
- Knowledge and attitudes towards antibiotics and antimicrobial resistance among patients in rural South Africa and the implications for future policies.Frontiers in pharmacology · 2026Article
- Mapping socioeconomic factors driving antimicrobial resistance in humans: An umbrella review.One health (Amsterdam, Netherlands) · 2025Review
- Knowledge and practices of healthcare professionals regarding antibiotic use in a district hospital, Southern Mozambique: a cross-sectional study.Scientific reports · 2025Article
- Status and implications of the knowledge, attitudes and practices towards AWaRe antibiotic use, resistance and stewardship among low- and middle-income countries.JAC-antimicrobial resistance · 2025Review
- Knowledge, attitude, and practices regarding antibiotic use and antimicrobial resistance among urban slum dwellers in Uganda.Antimicrobial resistance and infection control · 2025Article
- Behavioral and Socio-Economic Determinants of Antimicrobial Resistance in Sub-Saharan Africa: A Systematic Review.Infection and drug resistance · 2025Review
- A Decade of Antimicrobial Resistance in Human and AnimalAntibiotics (Basel, Switzerland) · 2024Review
- Relation of poverty with treatment-seeking behavior and antibiotic misuse among UTI patients in Pakistan.Frontiers in public health · 2024Article
- Knowledge, attitudes, and practices regarding antibiotic use in Bangladesh: Findings from a cross-sectional study.PloS one · 2024Article
- Sanitation in urban areas may limit the spread of antimicrobial resistance via flies.PloS one · 2024Article
- Knowledge, Attitudes, and Practices in Antibiotic Dispensing amongst Pharmacists in Trinidad and Tobago: Exploring a Novel Dichotomy of Antibiotic Laws.Antibiotics (Basel, Switzerland) · 2023Article
- Comparison of knowledge, attitude, practice and predictors of self-medication with antibiotics among medical and non-medical students in Tanzania.Frontiers in pharmacology · 2023Article
- Knowledge, Attitudes, and Practices (KAP) About Antibiotic Use in Hemodialysis Patients with Chronic Kidney Disease and Their Household Contacts, Medellín-Colombia.Infection and drug resistance · 2023Article
- Environmental bacterial and fungal contamination in high touch surfaces and indoor air of a paediatric intensive care unit in Maputo Central Hospital, Mozambique in 2018.Infection prevention in practice · 2022Article
- Non-prescribed antibiotic use for children at community levels in low- and middle-income countries: a systematic review and meta-analysis.Journal of pharmaceutical policy and practice · 2022Article
- Understanding parental self-medication with antibiotics among parents of different nationalities: a cross-sectional study.Global health research and policy · 2021Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIrrational use of antibiotics is a major driver of antimicrobial resistance (AMR) worldwide. Sub-Saharan Africa, where the risk of spread of AMR is highest, lacks data on the knowledge, attitudes and practices regarding antibiotic prescription and use. This is the first study in Mozambique to address this gap.
methodsA cross-sectional study was conducted in 2016 in 1091 adults (age ≥18 years) living in five districts in peri-urban areas of Maputo City. Three stage cluster sampling was used to select the households. A semi-structured questionnaire was used to collect information on the knowledge, attitudes and practices regarding antibiotics and their use and socio-demographic data.
resultsOf the 1091 participants, 20.9% (228/1091) had used non-prescribed antibiotics. Most of the non-prescribed antibiotics were purchased in pharmacies (199/228; 87.3%). The proportion of use of non-prescribed antibiotics was higher in those who purchased from informal markets (82.6%; 14/17) and home stores (66.7%; 12/18), compared to pharmacies (24.6%; 199/810) (p = 0.000). Variables significantly associated with use of non-prescribed antibiotics were male gender (p = 0.004), living in the Central A (p<0.001), Aeroporto B (p<0.001) or 25 de Junho (p<0.001) neighborhoods, purchase of antibiotics in informal markets (p<0.002) or obtaining from home stores (p = 0.026), not completing the course (p<0.001) and having poor knowledge on the use of antibiotics (p<0.001). Main reasons for use of non-prescribed antibiotics were a perception that there was no need to attend a health facility (26.8%), followed by someone else's advice (7.7%), symptoms similar to a previous episode (6.2%) and poor quality of care in health facilities (6.7%).
conclusionsOur study shows for the first time that knowledge regarding antibiotics is poor in Maputo City. Purchase of non-prescribed antibiotics is a common practice and most are sold in pharmacies, indicating deficient inspection. Interventions to reinforce adherence by pharmacies to current legislation for dispensing antibiotics, combined with community education are urgently needed.
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