Evidence map›Paper›PMID 31436914›Full record

ArticleJournal of cellular and molecular medicine2019

Cold-inducible protein RBM3 mediates hypothermic neuroprotection against neurotoxin rotenone via inhibition on MAPK signalling.

Hai-Jie Yang, Rui-Juan Zhuang, Yuan-Bo Li, Tian Li, Xin Yuan, Bing-Bing Lei, Yun-Fei Xie, Mian Wang

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. SMYD5 is a regulator of the mild hypothermia response.bioRxiv : the preprint server for biology · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. The mRNA-Binding Protein RBM3 Regulates Activity Patterns and Local Synaptic Translation in Cultured Hippocampal Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Research Progress of the Application of Hypothermia in the Eye.Oxidative medicine and cellular longevity · 2020
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Hai-Jie YangSchool of Life Science and Technology, Xinxiang Medical University, Xinxiang, China.
Rui-Juan ZhuangSchool of Pharmaceutical Sciences, Xiamen University, Xiamen, China.
Yuan-Bo LiSchool of Life Science and Technology, Xinxiang Medical University, Xinxiang, China.
Tian LiSchool of Life Science and Technology, Xinxiang Medical University, Xinxiang, China.
Xin YuanSchool of Life Science and Technology, Xinxiang Medical University, Xinxiang, China.
Bing-Bing LeiSchool of Life Science and Technology, Xinxiang Medical University, Xinxiang, China.
Yun-Fei XieSchool of Life Science and Technology, Xinxiang Medical University, Xinxiang, China.
Mian WangSchool of Life Science and Technology, Xinxiang Medical University, Xinxiang, China.ORCID 0000-0002-2861-2725
Xinxiang Medical University · CNHenan Psychiatric Hospital · CNXiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mild hypothermia and its key product, cold-inducible protein RBM3, possess robust neuroprotective effects against various neurotoxins. However, we previously showed that mild hypothermia fails to attenuate the neurotoxicity from MPP

Indexed as

Cold TemperatureApoptosisCell Line, TumorCytoprotectionEnzyme ActivationHumansHypothermia, InducedMAP Kinase Signaling SystemNeuroprotectionNeurotoxinsRNA-Binding ProteinsRotenoneNeurotoxinsRBM3 protein, humanRNA-Binding ProteinsRotenonehypothermiaMAPK signallingParkinson's diseaseRBM3rotenone

Identifiers

PMID31436914
PMCPMC6787511
OpenAlexW2969396912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.