ArticleChinese medical journal2019
Persistent depression is a predictor of quality of life in stroke survivors: results from a 5-year follow-up study of a Chinese cohort.
Article in Chinese medical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.
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16 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Association between Marital/Partner Status and Patient-Reported Outcomes in Stroke Patients: A Systematic Review.Cerebrovascular diseases (Basel, Switzerland) · 2026Pooled it
- Non-Invasive Brain Stimulation Progression in Post-Stroke Depression Treatment: A Systematic Review.Alpha psychiatry · 2024Pooled it
- Impact of depression on stroke outcomes among stroke survivors: Systematic review and meta-analysis.PloS one · 2023Pooled it
- Comparative evaluation of diffusion models for detecting gray matter microstructural alterations in post-stroke depression patients.Frontiers in neurology · 2026Article
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- The trajectory of depressive symptoms and the association with quality of life and suicidal ideation in patients with major depressive disorder.BMC psychiatry · 2025Article
- Genetic Polymorphisms and Gene-Environment Interactions in Persistent Post-Stroke Depression.Neuropsychiatric disease and treatment · 2025Article
- A higher burden of post-stroke depression and anxiety and their predictors among stroke survivors in the Amhara Regional State, Ethiopia, in 2024: a prospective multicenter study.Frontiers in psychiatry · 2025Article
- Nomogram for Persistent Post-Stroke Depression and Decision Curve Analysis.Clinical interventions in aging · 2022Article
- A Narrative Review on the Non-Pharmacologic Interventions in Post-Stroke Depression.Psychology research and behavior management · 2022Review
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- Early-Onset Depression in Stroke Patients: Effects on Unfavorable Outcome 5 Years Post-stroke.Frontiers in psychiatry · 2021Article
- Potential Factors for Psychological Symptoms at Three Months in Patients with Young Ischemic Stroke.BioMed research international · 2021Article
- Factors Affecting Quality of Life among Post-Stroke Patients in the Sub-Himalayan Region.Journal of neurosciences in rural practice · 2020Article
- Mild to Severe Depressive Symptoms in Elderly Stroke Survivors and Its Associated Factors: Evidence From a Cross-Sectional Study in Zhejiang Province, China.Frontiers in psychiatry · 2020Article
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6 authors.
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Abstract
backgroundWhether the time course of post-stroke depression (PSD) can be used to predict the quality of life (QoL) of patients with late-stage stroke remains unclear, this study investigated whether persistent depression at 1 year after stroke predicts QoL at 5 years following stroke.
methodsWe analyzed the demographic and clinical data of patients with stroke in 56 hospitals across China that participated in the Prospective Cohort Study on the Incidence and Outcome of Patients with PSD in China Study. Follow-up assessments were performed at the following time points after stroke: in person, 2 weeks, 3 months, 6 months, and 1 year; by telephone, 5 years. National Institutes of Health Stroke Scale (NIHSS) score on admission, recurrence, disability, depression, QoL, and chronic complications were recorded. Depression was diagnosed using the Diagnostic and Statistical Manual of Mental Disorders. QoL was measured using short form-12 (SF-12). Multivariable ordinal logistic regression analysis was used to identify factors that independently affected the physical component summary (PCS) and mental component summary (MCS) scores of the SF-12.
resultsOf the 801 patients evaluated in this study, 80 had persistent depression. The multivariable regression analysis of data obtained at 5 years showed that persistent depression at 1 year (odds ratio [OR]: 0.48; 95% confidence interval [CI]: 0.29-0.81) and disability at 5 years (OR: 0.34; 95% CI: 0.23-0.49) were associated with poor MCS scores at 5 years. Old age, a high NIHSS score on admission, disability at 5 years, and stroke recurrence within 5 years were associated with poor PCS scores at the 5-year follow-up.
conclusionsPersistent depression at the 1-year follow-up could predict poor MCS scores at the 5-year follow-up. The development of interventional strategies targeting post-stroke patients with persistent depression is warranted.
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