ReviewHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2019
Inflammation in multimorbidity and disability: An integrative review.
Review in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The impact of adverse childhood experiences on multimorbidity: a systematic review and meta-analysis.BMC medicine · 2024Pooled it
- Subclinical inflammation and early pathogenesis of rheumatic diseases: mechanistic insights relevant to primary care.Irish journal of medical science · 2026Review
- Perceived Neighborhood Disorder, Health Behaviors, and Inflammation Among Older Adults: A Mediation Analysis.Journal of aging and health · 2026Article
- The Inflammaging-Redox-InflammamiR Axis in Metabolic Aging: From Diagnostic Clusters to Integrated Risk Phenotypes.Biomolecules · 2026Review
- Chemotherapy-induced peripheral neuropathy and social interaction anxiety in breast cancer patients: a cross-sectional study.BMC women's health · 2026Article
- Accelerated multimorbidity in early adulthood and long-term functional disability in later life: a life-course epidemiological study.International journal for equity in health · 2026Article
- Early dynamics of multimorbidity in 17.4 million people in Spain: onset patterns and prognostic value.European journal of public health · 2026Article
- Association of multimorbidity and its patterns with incident possible sarcopenia among middle-aged and older adults: findings from a national prospective cohort study in China.BMC musculoskeletal disorders · 2026Article
- Effect of exercise therapy and self-management support on multimorbidity: Secondary analysis of the MOBILIZE trial.Communications medicine · 2026Article
- Article
- Drug-disease interactions in inflammation: mechanisms, clinical Impact, and future directions.Inflammopharmacology · 2026Review
- Genetic insights into number of long-term conditions and their relationship with lifespan.PloS one · 2026Article
- Association between body mass index and disability among older population in China: analysis of 2011-2020 data from the China Health and Retirement Longitudinal Study.Journal of global health · 2025Article
- The association between subjective well-being and physical-psychological-cognitive multimorbidity: a longitudinal analysis of a nationally representative survey.Scientific reports · 2025Article
- Multimorbidity quantification from the perspective of precision management: challenges and strategies.Annals of medicine · 2025Review
- Impact of multimorbidity on health-related quality of life: the mediation role of intrinsic capacity - evidence from the WHO ICOPE pilot program in Lianyungang of China (2024).Archives of public health = Archives belges de sante publique · 2025Article
- Bidirectional relationships between disability and cognitive decline: a 6-year longitudinal study.BMC geriatrics · 2025Article
- A novel DNA methylation-based surrogate biomarker for chronic systemic inflammation (Inflammation Latent Variable Methylation Surrogate, InfLaMeS).The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Association Between Age and Severity at Disability Onset and All-Cause Mortality: Longitudinal Observational Study From the Health and Retirement Study.JMIR aging · 2025Observational
- Healthcare-Associated Infections (HAIs) in the Elderly: Molecular Mechanisms of Immunosenescence and Clinical, Nutritional and Therapeutic Implications.International journal of molecular sciences · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
objectiveMultimorbidity is a robust predictor of disability in aging adults, but the mechanisms by which multimorbidity is disabling are not clear. Most existing research focuses on disease-specific phenomena, such as diminished lung capacity in chronic obstructive pulmonary disease, which can result in functional limitations. This review takes a different approach by highlighting the potential role of a biological process-inflammation-that is common to many chronic medical conditions and thus, from a medical perspective, relatively disease nonspecific.
methodBeginning with a description of inflammation and its measurement, this paper will provide an overview of research on inflammation as a predictor of disease risk in healthy adults and of adverse outcomes (e.g., disability) in those with multimorbidity.
resultsThe discussion of inflammation is then situated in the context of biopsychosocial influences on health, as inflammation has been shown to be sensitive to a wide range of social and psychological processes that are thought to contribute to healthy aging, including successful adaptation to multimorbidity and reduced risk of disability.
conclusionsFinally, implications of this broader perspective for interventions to improve outcomes in aging adults with multimorbidity are briefly considered. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.