Evidence map›Paper›PMID 31436209›Full record

ArticleIndian journal of ophthalmology2019

Intravitreal sustained-release dexamethasone implant for the treatment of persistent cystoid macular edema in ocular syphilis.

Parthopratim Dutta Majumder, Lakshmi Mayilvakanam, Amit H Palker, Sudharshan Sridharan, Jyotirmay Biswas

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Indian journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Persistent syphilitic ocular manifestations despite treatment: a case series.Journal of ophthalmic inflammation and infection · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Parthopratim Dutta MajumderDepartment of Uvea, Medical and Vision Research Foundations, Chennai, Tamil Nadu, India.
Lakshmi MayilvakanamDepartment of Uvea and Medical Retina, Medical and Vision Research Foundations, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Amit H PalkerDepartment of Uvea and Medical Retina, Medical and Vision Research Foundations, Sankara Nethralaya, Chennai, Tamil Nadu, India.
Sudharshan SridharanDepartment of Uvea, Medical and Vision Research Foundations, Chennai, Tamil Nadu, India.
Jyotirmay BiswasDepartment of Uvea, Medical and Vision Research Foundations, Chennai, Tamil Nadu, India.
Sankara Nethralaya · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With a resurgence of syphilis with human immunodeficiency virus (HIV) infection in last few years, various ocular manifestations of syphilis have been described in literature. This case report described an HIV-positive patient on anti-retroviral therapy who was diagnosed and treated for posterior uveitis secondary to ocular syphilis in the recent past presented to our clinic with cystoid macular edema (CME). CME, which did not respond to periocular corticosteroid, resolved with intravitreal sustained release dexamethasone implant. There was a recurrence CME 9 months later and repeat injection of intravitreal implant showed complete resolution. A long-term follow-up did not reveal reactivation of the infection with intravitreal corticosteroid. Intravitreal sustained release dexamethasone implant can be an effective treatment for refractory CME in patients with regressed syphilitic uveitis.

Indexed as

AdultDelayed-Action PreparationsDexamethasoneDrug ImplantsEye Infections, BacterialFollow-Up StudiesGlucocorticoidsHumansIntravitreal InjectionsMacular EdemaMaleSyphilisTomography, Optical CoherenceDelayed-Action PreparationsDexamethasoneDrug ImplantsGlucocorticoidsCystoid macular edemahuman immunodeficiency virusintravitreal corticosteroidocular syphilisrapid plasma reagin

Identifiers

PMID31436209
PMCPMC6727693
OpenAlexW2970273813

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.