ArticleHuman brain mapping2019
Structural connectivity profile supports laterality of the salience network.
Article in Human brain mapping, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
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- Central autonomic network dysfunction in Stroke-Heart Syndrome: mechanistic roles of the insula and limbic system.Frontiers in neuroscience · 2026Review
- Structural and functional connectivity associations with anterior cingulate sulcal variability.Brain structure & function · 2024Article
- A diffusion MRI tractography atlas for concurrent white matter mapping across Eastern and Western populations.Scientific data · 2024Article
- Structural and functional connectivity associations with anterior cingulate sulcal variability.Research square · 2024Article
- Structural brain network lateralization across childhood and adolescence.Human brain mapping · 2023Article
- The contralateral effects of anticipated stimuli on brain activity measured by ERP and fMRI.Psychophysiology · 2023Article
- Anterior cingulate sulcation is associated with onset and survival in frontotemporal dementia.Brain communications · 2023Article
- Front and center: Maturational dysregulation of frontal lobe functional neuroanatomic connections in attention deficit hyperactivity disorder.Frontiers in neuroanatomy · 2022Article
- Prefrontal connectomics: from anatomy to human imaging.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022Review
- Role of amygdala in stress-induced upregulation of airway IL-1 signaling in asthma.Biological psychology · 2022Article
- Spatial and Temporal Distribution of Information Processing in the Human Dorsal Anterior Cingulate Cortex.Frontiers in human neuroscience · 2022Article
- Neural correlates of individual variation in two-back working memory and the relationship with fluid intelligence.Scientific reports · 2021Article
- Right Frontoinsular Cortex: A Potential Imaging Biomarker to Evaluate T2DM-Induced Cognitive Impairment.Frontiers in aging neuroscience · 2021Article
- Self-reference Network-Related Interactions During the Process of Cognitive Impairment in the Early Stages of Alzheimer's Disease.Frontiers in aging neuroscience · 2021Article
- Frequency-dependent circuits anchored in the dorsal and ventral left anterior insula.Scientific reports · 2020Article
- Sex Differences in Salience Network Connectivity and its Relationship to Sensory Over-Responsivity in Youth with Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2020Article
- Structural connectivity profile supports laterality of the salience network.Human brain mapping · 2019Article
- Surgical and oncological score to estimate the survival benefit of resection and chemoradiotherapy in elderly (≥70 years) glioblastoma patients: A preliminary analysis.Neuro-oncology advancesArticle
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Authors and funding
6 authors.
Funding
Abstract
The salience network (SN) is mainly involved in detecting and filtering multimodal salient stimuli, and mediating the switch between the default mode network and central executive network. Early studies have indicated a right-sided dominance in the functional organization of the SN; however, the anatomical basis of the functional lateralization remains unclear. Here, we hypothesized that the structural connectivity profile between the frontoinsular cortex (FIC) and dorsal anterior cingulate cortex (dACC), which are two core hubs of the SN, is also dominant in the right hemisphere. Based on diffusion and resting-state functional magnetic resonance imaging (rfMRI) of adult healthy volunteers in independent datasets, we found a stable right-sided laterality of both the FIC-dACC structural and functional connectivity in both the human connectome project cohort and a local Chinese cohort. Furthermore, a significant effect of aging on the integrity of the right FIC-dACC structural connectivity was also identified. The right-sided laterality of the structural organization of the SN may help us to better understand the functional roles of the SN in the normal human brain.
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