Evidence map›Paper›PMID 31435765›Full record

ArticleParasitology research2019

Molecular identification of cystic echinococcosis in humans and pigs reveals the presence of both Echinococcus granulosus sensu stricto and Echinococcus canadensis G6/G7 in the hyperendemic focus of the Republic of Moldova.

Gérald Umhang, Oleg Chihai, Vanessa Bastid, Florence Elisabeth Grenouillet, Dumitru Erhan, Adrian Hotineanu, Vera Lungu, Stefan Rusu, Frédéric Grenouillet, Franck Boue

Open access · goldAbstract read
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In one paragraph

Article in Parasitology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Gérald UmhangNancy Laboratory for Rabies and Wildlife, National Reference Laboratory for Echinococcus spp., Wildlife Surveillance and Eco-epidemiology Unit, ANSES, Technopôle Agricole et Vétérinaire, 40009, 54220, Malzéville, France. gerald.umhang@anses.fr.ORCID http://orcid.org/0000-0001-6944-7474
Oleg ChihaiInstitute of Zoology, Academy of Sciences of Moldova, Chisinău, Republic of Moldova.
Vanessa BastidNancy Laboratory for Rabies and Wildlife, National Reference Laboratory for Echinococcus spp., Wildlife Surveillance and Eco-epidemiology Unit, ANSES, Technopôle Agricole et Vétérinaire, 40009, 54220, Malzéville, France.
Florence Elisabeth GrenouilletParasite and Fungal Serologies Unit, French National Reference Center for Alveolar Echinococcosis and WHO Collaborating Center for Prevention and Treatment of Human Echinococcosis, University Hospital, Besançon, France.
Dumitru ErhanInstitute of Zoology, Academy of Sciences of Moldova, Chisinău, Republic of Moldova.
Adrian HotineanuHepatobiliopancreatic Department, Republican Clinical Hospital "Timofei Mosneaga", Chisinău, Republic of Moldova.
Vera LunguParasitic Surveillance Division, National Center of Public Health, Chisinău, Republic of Moldova.
Stefan RusuInstitute of Zoology, Academy of Sciences of Moldova, Chisinău, Republic of Moldova.
Frédéric GrenouilletParasite and Fungal Serologies Unit, French National Reference Center for Alveolar Echinococcosis and WHO Collaborating Center for Prevention and Treatment of Human Echinococcosis, University Hospital, Besançon, France.
Franck BoueNancy Laboratory for Rabies and Wildlife, National Reference Laboratory for Echinococcus spp., Wildlife Surveillance and Eco-epidemiology Unit, ANSES, Technopôle Agricole et Vétérinaire, 40009, 54220, Malzéville, France.
Academy of Sciences of Moldova · MDLife Services (United States) · USCentre National de la Recherche Scientifique · FRPhthisiopneumology Institute "Chiril Draganiuc" · MD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystic echinococcosis is caused by the parasitic species of the complex Echinococcus granulosus sensu lato. This disease is hyperendemic in the Republic of Moldova. Recent molecular analyses have revealed the exclusive presence of E. granulosus sensu stricto in sheep and cattle. Previous reports of prevalence in pigs suggest the potential presence of Echinococcus canadensis G6/G7, as this species is also reported in neighboring countries. The presence of cystic echinococcosis in pigs was specifically monitored at the slaughterhouse. In the meantime, human cases were genotyped for the first time. E. canadensis G6/G7 was identified in all ten pigs infected by E. granulosus s.l. One human case of infection by E. canadensis G6/G7 was also identified, while E. granulosus sensu stricto was found to be the cause for the 13 others. The description of one human case of E. canadensis G6/G7 has confirmed its zoonotic impact in the country. Future studies will be needed to estimate the relative proportion and distribution of both parasitic species in Moldova.

Indexed as

AbattoirsAnimalsCattleCystsEchinococcosisEchinococcus granulosusGenotypeHumansMoldovaPrevalenceSwineSwine DiseasesZoonosesCystic echinococcosisEchinococcus canadensis G6/G7Echinococcus granulosus sensu strictoHumanPig

Identifiers

PMID31435765
OpenAlexW2969736762

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.