Evidence map›Paper›PMID 31435696›Full record

ReviewThe Journal of membrane biology2019

Membrane Dynamics in Health and Disease: Impact on Cellular Signalling.

Pranav Adhyapak, Shobhna Kapoor

Abstract readReview
PubMed Publisher
In one paragraph

Review in The Journal of membrane biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Phospholipids: Identification and Implication in Muscle Pathophysiology.International journal of molecular sciences · 2021
    Review
  5. Special Issue: Membrane and Receptor Dynamics.The Journal of membrane biology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Pranav AdhyapakDepartment of Chemistry, Indian Institute of Technology Bombay, Powai, 400076, India.
Shobhna KapoorDepartment of Chemistry, Indian Institute of Technology Bombay, Powai, 400076, India. shobhnakapoor@chem.iitb.ac.in.ORCID 0000-0003-3684-4312
Indian Institute of Technology Bombay · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biological membranes display a staggering complexity of lipids and proteins orchestrating cellular functions. Superior analytical tools coupled with numerous functional cellular screens have enabled us to query their role in cellular signalling, trafficking, guiding protein structure and function-all of which rely on the dynamic membrane lipid properties indispensable for proper cellular functions. Alteration of these has led to emergence of various pathological conditions, thus opening an area of lipid-centric therapeutic approaches. This perspective is a short summary of the dynamic properties of membranes essential for proper cellular functions, dictating both protein and lipid functions, and mis-regulated in diseases. Towards the end, we focus on some challenges lying ahead and potential means to tackle the same, mainly underscored by multi-disciplinary approaches.

Indexed as

Signal TransductionAnimalsCell MembraneHumansMembrane LipidsMembrane ProteinsProtein TransportMembrane LipidsMembrane ProteinsLipid diffusionLipid domainsLipid-protein interactionsMembrane lipid structureMembrane-targeting drugs

Identifiers

PMID31435696
OpenAlexW2969455108

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.