ReviewInternational journal of reproductive biomedicine2019
The comparison of depression and anxiety between fertile and infertile couples: A meta-analysis study.
Review in International journal of reproductive biomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07154888 (Fast Track to Fertility), which is not on this map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Fast Track to Fertility: Randomized Controlled Quality Improvement Initiative of an Algorithmic Text Messaging Communication and Patient Education Platform Designed to Improve the Efficiency the Fertility Workup
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- Attachment Dimensions and Infertility: Exploring Psychological Outcomes Through Systematic Review and Meta-Analysis.Journal of marital and family therapy · 2025Pooled it
- Timed intercourse for couples trying to conceive.The Cochrane database of systematic reviews · 2023Pooled it
- Psychological aspects of infertility. A systematic review.The Journal of international medical research · 2020Pooled it
- The effect of cognitive behavior therapy on attitude of infertile individuals toward child adoption.Journal of preventive medicine and hygiene · 2022Trial
- The effect of inhalation aromatherapy with lemon balm essential oil on perceived stress in infertile women undergoing in vitro fertilization: An RCT.International journal of reproductive biomedicine · 2025Article
- Factors influencing the anxiety and depression status in patients undergoing in vitro fertilization-embryo transfer assisted pregnancy.Scientific reports · 2025Article
- Effectiveness of Low-Cost, Virtual Sexual Health Education and Educational Leaflets on Reducing Anxiety and Enhancing Sexual Function Among Infertile Women: A Pilot Randomized Controlled Trial.Health science reports · 2025Article
- Prevalence of Depression Among Infertile Women at Center for Fertility and Reproductive Medicine in Ethiopia: A Cross-Sectional Study.Health science reports · 2025Article
- Infertility stigma and openness with others are related to depressive symptoms and meaning in life in men and women diagnosed with infertility.Reproductive health · 2025Article
- Long term exposure to road traffic noise and air pollution and risk of infertility in men and women: nationwide Danish cohort study.BMJ (Clinical research ed.) · 2024Article
- Article
- Acupuncture Treatment for Emotional Problems in Women with Infertility: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2023Review
- Sexual growth and destiny beliefs: Longitudinal associations with dyadic coping among couples seeking medically assisted reproduction.The journal of sexual medicine · 2023Article
- Exposure to perfluoroalkyl substances and women's fertility outcomes in a Singaporean population-based preconception cohort.The Science of the total environment · 2023Article
- Article
- Investigating the role of defense mechanisms on marital adjustment in infertile couples based on the cause of infertility: A cross-sectional study.International journal of reproductive biomedicine · 2023Article
- Predicting the dyadic coping through self-esteem among infertile couples undergoingFrontiers in psychology · 2023Article
- Cortisol dysregulation in anxiety infertile women and the influence on IVF treatment outcome.Frontiers in endocrinology · 2023Article
- Prevalence and predictive factors for infertility-related stress among infertile couples: A cross-sectional study from Jordan and the occupied Palestinian territories.Saudi medical journal · 2022Article
- Impact of Stress and Financials on Romanian Infertile Women Accessing Assisted Reproductive Treatment.International journal of environmental research and public health · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDepression and anxiety are the most common reaction in infertile couples. Several studies have been conducted to examine the psychiatric disorders among infertile and fertile couples.
objectiveThis meta-analysis was conducted to compare the depression and anxiety in fertile and infertile couples in various studies. MATERIALS AND
methodsThe authors searched articles published in multiple databases including World Health Organization, PubMed, Cochrane Library, Scopus, Science Direct, Medline EMBASE and Persian databases including Scientific Information Database (SID) and IranMedx between 2005 and 2017. The main keywords used for searching the databases were: depression, anxiety, infertility, and fertility. Statistical analyses were performed using Comprehensive Meta-Analysis/2.0 software.
resultsThe authors found 42 related articles after searching the databases. 11 articles entered the meta-analysis after considering the inclusion and exclusion criteria. Finally, eight articles were chosen for the comparison of depression and anxiety, two published articles for the comparison of depression, and one published article to compare anxiety in fertile and infertile couples. The results of the heterogeneity test showed a significant heterogeneity among all articles that were analyzed in this meta-analysis in the field of depression and anxiety. The results showed that depression (p = 0.0001; Hedges'g = 1.21; 95% CI 0.63-1.78) and anxiety (p = 0.00001; Hedges'g = 0.63; 95% CI 0.54-0.73) were higher in infertile couples than fertile couples and that the possibility of a publication bias does not exist in this study.
conclusionThe analysis of articles used in this meta-analysis showed that depression and anxiety scores in infertile couples were higher than fertile couples.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.