Evidence map›Paper›PMID 31435571›Full record

ArticleSpine surgery and related research2019

Risk Factors for Proximal Junctional Fracture Following Fusion Surgery for Osteoporotic Vertebral Collapse with Delayed Neurological Deficits: A Retrospective Cohort Study of 403 Patients.

Koji Tamai, Hidetomi Terai, Akinobu Suzuki, Hiroaki Nakamura, Kei Watanabe, Keiichi Katsumi, Masayuki Ohashi, Yohei Shibuya, Tomohiro Izumi, Toru Hirano and 60 more

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Article in Spine surgery and related research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Osteoporosis and osteoporosis therapies as determinants of implant fixation failure in arthroplasty and spinal fusion constructs: a position statement from the Fracture Working Group of the Council of Scientific Advisors of the International Osteoporosis Foundation.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

70 authors.

Koji TamaiDepartment of Orthopaedic Surgery, Osaka City University, Osaka City, Japan.
Hidetomi TeraiDepartment of Orthopaedic Surgery, Osaka City University, Osaka City, Japan.
Akinobu SuzukiDepartment of Orthopaedic Surgery, Osaka City University, Osaka City, Japan.
Hiroaki NakamuraDepartment of Orthopaedic Surgery, Osaka City University, Osaka City, Japan.
Kei WatanabeDepartment of Orthopaedic Surgery, Niigata University, Niigata City, Japan.
Keiichi KatsumiDepartment of Orthopaedic Surgery, Niigata University, Niigata City, Japan.
Masayuki OhashiDepartment of Orthopaedic Surgery, Niigata University, Niigata City, Japan.
Yohei ShibuyaDepartment of Orthopaedic Surgery, Niigata University, Niigata City, Japan.
Tomohiro IzumiDepartment of Orthopaedic Surgery, Niigata University, Niigata City, Japan.
Toru HiranoDepartment of Orthopaedic Surgery, Niigata University, Niigata City, Japan.
Takashi KaitoDepartment of Orthopaedic Surgery, Osaka University, Suita City, Japan.
Tomoya YamashitaDepartment of Orthopaedic Surgery, Osaka University, Suita City, Japan.
Hiroyasu FujiwaraDepartment of Orthopaedic Surgery, Osaka University, Suita City, Japan.
Yukitaka NagamotoDepartment of Orthopaedic Surgery, Osaka University, Suita City, Japan.
Yuji MatsuokaDepartment of Orthopaedic Surgery, Tokyo Medical University, Tokyo, Japan.
Hidekazu SuzukiDepartment of Orthopaedic Surgery, Tokyo Medical University, Tokyo, Japan.
Hirosuke NishimuraDepartment of Orthopaedic Surgery, Tokyo Medical University, Tokyo, Japan.
Atsushi TagamiDepartment of Orthopaedic Surgery, Nagasaki University, Nagasaki City, Japan.
Syuta YamadaDepartment of Orthopaedic Surgery, Nagasaki University, Nagasaki City, Japan.
Shinji AdachiDepartment of Orthopaedic Surgery, Nagasaki University, Nagasaki City, Japan.
Toshitaka YoshiiDepartment of Orthopaedic Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Shuta UshioDepartment of Orthopaedic Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Katsumi HarimayaDepartment of Orthopaedic Surgery, Kyushu University, Fukuoka city, Japan.
Kenichi KawaguchiDepartment of Orthopaedic Surgery, Kyushu University, Fukuoka city, Japan.
Nobuhiko YokoyamaDepartment of Orthopaedic Surgery, Kyushu University, Fukuoka city, Japan.
Hidekazu OishiDepartment of Orthopaedic Surgery, Kyushu University, Fukuoka city, Japan.
Toshiro DoiDepartment of Orthopaedic Surgery, Kyushu University, Fukuoka city, Japan.
Atsushi KimuraDepartment of Orthopaedic Surgery, Jichi Medical University, Shimotsuke city, Japan.
Hirokazu InoueDepartment of Orthopaedic Surgery, Jichi Medical University, Shimotsuke city, Japan.
Gen InoueDepartment of Orthopaedic Surgery, Kitasato University, Sagamihara city, Japan.
Masayuki MiyagiDepartment of Orthopaedic Surgery, Kitasato University, Sagamihara city, Japan.
Wataru SaitoDepartment of Orthopaedic Surgery, Kitasato University, Sagamihara city, Japan.
Atsushi NakanoDepartment of Orthopaedic Surgery, Osaka Medical College, Takatsuki city, Japan.
Daisuke SakaiDepartment of Orthopaedic Surgery, Tokai University, Isehara city, Japan.
Tadashi NukagaDepartment of Orthopaedic Surgery, Tokai University, Isehara city, Japan.
Shota IkegamiDepartment of Orthopaedic Surgery, Shinshu University, Matsumoto city, Japan.
Masayuki ShimizuDepartment of Orthopaedic Surgery, Shinshu University, Matsumoto city, Japan.
Toshimasa FutatsugiDepartment of Orthopaedic Surgery, Shinshu University, Matsumoto city, Japan.
Seiji OhtoriDepartment of Orthopaedic Surgery, Chiba University, Chiba city, Japan.
Takeo FuruyaDepartment of Orthopaedic Surgery, Chiba University, Chiba city, Japan.
Sumihisa OritaDepartment of Orthopaedic Surgery, Chiba University, Chiba city, Japan.
Shiro ImagamaDepartment of Orthopaedic Surgery, Nagoya University, Nagoya city, Japan.
Kei AndoDepartment of Orthopaedic Surgery, Nagoya University, Nagoya city, Japan.
Kazuyoshi KobayashiDepartment of Orthopaedic Surgery, Nagoya University, Nagoya city, Japan.
Katsuhito KiyasuDepartment of Orthopaedic Surgery, Kochi University, Nankoku city, Japan.
Hideki MurakamiDepartment of Orthopaedic Surgery, Kanazawa University, Kanazawa city, Japan.
Katsuhito YoshiokaDepartment of Orthopaedic Surgery, Kanazawa University, Kanazawa city, Japan.
Shoji SekiDepartment of Orthopaedic Surgery, University of Toyama, Toyama city, Japan.
Michio HongoDepartment of Orthopaedic Surgery, Akita University, Akita city, Japan.
Kenichiro KakutaniDepartment of Orthopaedic Surgery, Kobe University, Kobe city, Japan.
Takashi YurubeDepartment of Orthopaedic Surgery, Kobe University, Kobe city, Japan.
Yasuchika AokiDepartment of Orthopaedic Surgery, Eastern Chiba Medical Center, Togane city, Japan.
Masashi OshimaDepartment of Orthopaedic Surgery, Nihon University Itabashi Hospital, Tokyo, Japan.
Masahiko TakahataDepartment of Orthopaedic Surgery, Hokkaido University, Sapporo city, Japan.
Akira IwataDepartment of Orthopaedic Surgery, Hokkaido University, Sapporo city, Japan.
Hirooki EndoDepartment of Orthopaedic Surgery, Iwate Medical University, Morioka city, Japan.
Tetsuya AbeDepartment of Orthopaedic Surgery, University of Tsukuba, Tsukuba city, Japan.
Toshinori TsukanishiDepartment of Orthopaedic Surgery, University of Tsukuba, Tsukuba city, Japan.
Kazuyoshi NakanishiDepartment of Orthopaedic Surgery, Hiroshima University, Hiroshima city, Japan.
Kota WatanabeDepartment of Orthopaedic Surgery, Keio University, Tokyo, Japan.
Tomohiro HikataDepartment of Orthopaedic Surgery, Keio University, Tokyo, Japan.
Satoshi SuzukiDepartment of Orthopaedic Surgery, Keio University, Tokyo, Japan.
Norihiro IsogaiDepartment of Orthopaedic Surgery, Keio University, Tokyo, Japan.
Eijiro OkadaDepartment of Orthopaedic Surgery, Keio University, Tokyo, Japan.
Haruki FunaoDepartment of Orthopaedic Surgery, Keio University, Tokyo, Japan.
Seiji UedaDepartment of Orthopaedic Surgery, Keio University, Tokyo, Japan.
Yuta ShionoDepartment of Orthopaedic Surgery, Keio University, Tokyo, Japan.
Kenya NojiriDepartment of Orthopaedic Surgery, Keio University, Tokyo, Japan.
Naobumi HosoganeDepartment of Orthopaedic Surgery, National Defense Medical College, Tokorozawa city, Japan.
Ken IshiiDepartment of Orthopaedic Surgery, Keio University, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionApproximately 3% of osteoporotic vertebral fractures develop osteoporotic vertebral collapse (OVC) with neurological deficits, and such patients are recommended to be treated surgically. However, a proximal junctional fracture (PJFr) following surgery for OVC can be a serious concern. Therefore, the aim of this study is to identify the incidence and risk factors of PJFr following fusion surgery for OVC.

methodsThis study retrospectively analyzed registry data collected from facilities belonging to the Japan Association of Spine Surgeons with Ambition (JASA) in 2016. We retrospectively analyzed 403 patients who suffered neurological deficits due to OVC below T10 and underwent corrective surgery; only those followed up for ≥2 years were included. Potential risk factors related to the PJFr and their cut-off values were calculated using multivariate logistic regression analysis and receiver operating characteristic (ROC) analysis.

resultsSixty-three patients (15.6%) suffered PJFr during the follow-up (mean 45.7 months). In multivariate analysis, the grade of osteoporosis (grade 2, 3: adjusted odds ratio (aOR) 2.92; p=0.001) and lower instrumented vertebra (LIV) level (sacrum: aOR 6.75; p=0.003) were independent factors. ROC analysis demonstrated that lumbar bone mineral density (BMD) was a predictive factor (area under curve: 0.72, p=0.035) with optimal cut-off value of 0.61 g/cm

conclusionsPJFr was found in 16% cases within 4 years after surgery; independent risk factors were severe osteoporosis and extended fusion to the sacrum. The lumbar BMD with cut-off value 0.61 g/cm

Indexed as

corrective surgeryOsteoporosisproximal junctional fractureproximal junctional kyphosisvertebral fracture

Identifiers

PMID31435571
PMCPMC6690093

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.