ArticleSpine surgery and related research2019
Quantitative Analysis Concerning Atrophy and Fat Infiltration of the Multifidus Muscle with Magnetic Resonance Spectroscopy in Chronic Low Back Pain.
Article in Spine surgery and related research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Imaging Evaluation of Fat Infiltration in Paraspinal Muscles on MRI: A Systematic Review with a Focus on Methodology.Orthopaedic surgery · 2021Pooled it
- Development and reliability of a systematic method to evaluate lumbar paraspinal muscle size and quality in computed tomography images.North American Spine Society journal · 2025Article
- Assessment of the Fascial System Thickness in Patients with and Without Low Back Pain: A Narrative Review.Diagnostics (Basel, Switzerland) · 2025Review
- Correlation and risk factor analysis of multifidus muscle atrophy in degenerative lumbar spondylolisthesis.Frontiers in medicine · 2025Article
- Association of Preoperative Osteoporotic Vertebral Compression Fractures with Muscle Atrophy in Lumbar Spinal Stenosis: A Retrospective Cohort Study.Progress in rehabilitation medicine · 2024Article
- Article
- Risk Factors in Patients with Low Back Pain Under 40 Years Old: Quantitative Analysis Based on Computed Tomography and Magnetic Resonance Imaging mDIXON-Quant.Journal of pain research · 2023Article
- The relationship between the degeneration and asymmetry of the lumbar multifidus and erector spinae muscles in patients with lumbar disc herniation with and without root compression.Journal of orthopaedic surgery and research · 2022Article
- Factors associated with low back pain in patients with lumbar spinal stenosis: a cross-sectional study.BMC musculoskeletal disorders · 2022Article
- Magnetic Resonance Imaging Documentation of Approach Trauma With Lumbar Endoscopic Interlaminar, Translaminar, Compared to Open Microsurgical Discectomy.International journal of spine surgery · 2022Article
- Relationship between fatty infiltration of paraspinal muscles and clinical outcome after lumbar discectomy.Brain & spine · 2022Article
- Risk Factor Analysis for Fat Infiltration in the Lumbar Paraspinal Muscles in Patients With Lumbar Degenerative Diseases.Geriatric orthopaedic surgery & rehabilitation · 2022Article
- Efficacy of lumbar kinetic chain training for staged rehabilitation after percutaneous endoscopic lumbar discectomy.BMC musculoskeletal disorders · 2021Article
- Correlation between Psoas Muscle Index and Degeneration of Spinal Back Muscle in Patients with Back Pain.Healthcare (Basel, Switzerland) · 2021Article
- Paraspinal muscle pathophysiology associated with low back pain and spine degenerative disorders.JOR spine · 2021Review
- Magnetic Resonance Spectroscopic Analysis of Multifidus Muscle Lipid Contents and Association with Nociceptive Pain in Chronic Low Back Pain.Asian spine journal · 2021Article
- Inter-rater reliability between two examiners with different professional roles in the evaluation of fat infiltration in the lumbar paraspinal muscles using magnetic resonance imaging.Journal of physical therapy science · 2021Article
- Slacklining as therapy to address non-specific low back pain in the presence of multifidus arthrogenic muscle inhibition.World journal of orthopedics · 2021Review
- Is the Lipid Content of the Psoas Major Correlated with Chronic Low Back Pain and Spinopelvic Alignment? A Magnetic Resonance Spectroscopic Study.Asian spine journal · 2020Article
- Association between Spinopelvic Alignment and Lumbar Intervertebral Disc Degeneration Quantified with Magnetic Resonance Imaging T2 Mapping in Patients with Chronic Low Back Pain.Spine surgery and related research · 2020Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMagnetic resonance spectroscopy (MRS) enables detailed analysis of the composition of muscular fat tissues such as intramyocellular lipids (IMCLs) and extramyocellular lipids (EMCLs). The aim of this study was to analyze the EMCL and IMCL of the multifidus muscle (Mm) using MRS in chronic low-back pain (CLBP) patients and identify their possible correlations with age, body mass index (BMI), low-back pain (LBP) visual analog scale (VAS) score, cross-sectional area (CSA), and fat infiltration of the Mm.
methodsEighty patients (32 men and 48 women; mean age, 64.7 ± 1.3 years; range, 22-83 years) with VAS scores >30 mm for CLBP were included. We analyzed the gender difference and the possible correlations of age, BMI, LBP VAS, CSA, and fat infiltration of the Mm with the IMCL and EMCL of the Mm. The subjects were divided into five groups as per their age range: < 40s, 50s, 60s, 70s, and 80s. We also analyzed the EMCL and IMCL of the Mm as per the fat infiltration classification.
resultsCSA was larger in the male group, EMCL was higher in the female group, and there was no significant difference in IMCL between the female and male groups. There was a significant positive correlation of EMCL with age (r = 0.33,
conclusionsThese results suggest that EMCL could indicate Mm degeneration associated with aging, and IMCL could be an effective objective indicator of CLBP. The EMCL and IMCL of the Mm may be useful prognostic markers in rehabilitation strategies.
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