Evidence map›Paper›PMID 31435408›Full record

ArticleJournal of Taibah University Medical Sciences2019

Chromatographic and computational studies of ligands associated with bilharziasis.

Abdulazeez A Abubakar, Temidayo D Adeniyi, Ismaila O Nurain, Ayoade B Olanrewaju, Kareemat E Uthman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Taibah University Medical Sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Abdulazeez A AbubakarDepartment of Medical Laboratory Science, University of Medical Sciences, Ondo-City, Nigeria.
Temidayo D AdeniyiDepartment of Medical Laboratory Science, Kwara State University, Malete, Ilorin, Nigeria.
Ismaila O NurainDepartment of Biochemistry and Pharmacology, Kwara State University, Malete, Ilorin, Nigeria.
Ayoade B OlanrewajuDepartment of Medical Laboratory Science, Kwara State University, Malete, Ilorin, Nigeria.
Kareemat E UthmanDepartment of Medical Laboratory Science, Kwara State University, Malete, Ilorin, Nigeria.
Kwara State University · NGOndo State University of Science and Technology · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveRapid diagnostic techniques that do not depend on microscopic analysis are urgently needed for rapid diagnosis and management of bilharziasis. Specific ligands that are excreted through urine in bilharziasis may serve as rapid diagnostic biomarkers to replace microscopy, which is cumbersome and time-consuming. The aim of this study was to identify ligands associated with bilharziasis.

methodsMicroscopy was employed to detect ova of

resultsGC-MS revealed that the level of indole in bilharziasis sample was higher than that in normal urine. Indole was the ligand with the highest (28.63%) concentration in the pooled positive urine sample, while ethyl phenazone level was the highest (69.64%) in the pooled normal sample. Computational analysis depicted perfect docking with indole and all other ligands identified in positive urine samples.

conclusionThis study identified some ligands associated with bilharziasis some unique to normal (negative) urine samples.

Indexed as

Associated ligandsBilharziasisChromatographicComputational

Identifiers

PMID31435408
PMCPMC6695072
OpenAlexW2921597457

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.