ArticleJournal of Taibah University Medical Sciences2018
Therapeutic effects of balanitoside in streptozotocin-induced diabetic rats.
Article in Journal of Taibah University Medical Sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 20 citations in OpenAlex.
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- Inflammatory atherosclerotic plaque identification by SPECT/CT imaging of LFA-1 using [Annals of nuclear medicine · 2023Article
- Melatonin downregulates the increased hepatic alpha-fetoprotein expression and restores pancreatic beta cells in a streptozotocin-induced diabetic rat model: a clinical, biochemical, immunohistochemical, and descriptive histopathological study.Frontiers in veterinary science · 2023Article
- Fustin ameliorates hyperglycemia in streptozotocin induced type-2 diabetes via modulating glutathione/Superoxide dismutase/Catalase expressions, suppress lipid peroxidation and regulates histopathological changes.Saudi journal of biological sciences · 2021Article
- Hypoglycemic and hypolipidemic activities of phlorizin fromFood science & nutrition · 2021Article
- Phytochemicals and Biological Activity of Desert Date (Plants (Basel, Switzerland) · 2020Review
- Mormodica charantia L. fruit and Genistein ameliorates type 2 diabetes in rats by preventing lipid accumulation, insulin resistance and enhancing beta cell function.Journal of diabetes and metabolic disorders · 2020Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe objective of this study was to evaluate the therapeutic effects of balanitoside in diabetic rats.
methodsTwenty-five rats were divided into five groups. Rats in groups 2 to 5 were treated with streptozotocin to induce hyperglycemia. In addition, rats in groups 1 and 2 received 1 mL of distilled water, whereas those in groups 3, 4, and 5 received 10 and 20 mg/kg balanitoside and 6 U/kg insulin, respectively, for 14 days. All rats were sacrificed on day 15, blood samples were collected, and serum levels of alkaline phosphatase (ALP), alanine aminotransferase (ALT), and aspartate aminotransferase (AST) were measured. The liver was processed for examination under a light microscope.
resultsThe results showed a significant decrease in liver protein concentrations in diabetic control rats, compared to those in the normal control rats and rats treated with 10 mg/kg balanitoside (
conclusionThe findings of this study suggest the therapeutic effects of balanitoside in the liver of diabetic rats.
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