Evidence map›Paper›PMID 31435241›Full record

ReviewJournal of Taibah University Medical Sciences2017

Epigenetics of human diseases and scope in future therapeutics.

Monis B Shamsi, Abdul S Firoz, Syed N Imam, Naweed Alzaman, Muhammad A Samman

Open access · goldAbstract readReview
In one paragraph

Review in Journal of Taibah University Medical Sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

  1. COVID-19 and Interstitial Lung Disease.Medicina (Kaunas, Lithuania) · 2025
    Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. MIAOME: Human microbiome affect the host epigenome.Computational and structural biotechnology journal · 2022
    Article
  11. Article
  12. Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Monis B ShamsiCenter for Genetics & Inherited Diseases, Taibah University, Almadinah Almunawwarah, KSA.
Abdul S FirozCenter for Genetics & Inherited Diseases, Taibah University, Almadinah Almunawwarah, KSA.
Syed N ImamDepartment of Anatomy, College of Medicine, Taibah University, Almadinah Almunawwarah, KSA.
Naweed AlzamanDepartment of Internal Medicine, College of Medicine, Taibah University, Almadinah Almunawwarah, KSA.
Muhammad A SammanCenter for Genetics & Inherited Diseases, Taibah University, Almadinah Almunawwarah, KSA.
Taibah University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epigenetics is the study of nucleotide modifications that are heritable and act as regulatory mechanisms without changing the nucleotide sequence of the genome. Exogenous cues such as environment, lifestyle, nutrition, stress, and psychological factors affect epigenetic mechanisms. This mechanism is in concordance with the genetic information that plays an important role during prenatal and postnatal life of an individual. Recent epigenetic studies have revealed the potential of epigenetics in elucidating the mechanisms of different diseases. In this review, we discuss basic epigenetic mechanisms and their roles in health and disease. In addition, reported aberrations in epigenetic regulation for some common human diseases are described. Finally, we address some epigenetic approaches that have shown potential for targeted treatment of diseases.

Indexed as

Alzheimer's diseaseCancerDiabetesEpigeneticsImprinting disorders

Identifiers

PMID31435241
PMCPMC6695077
OpenAlexW2617832944

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.