ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2019
Clinical Profile and Outcome of Dengue Fever in Multidisciplinary Intensive Care Unit of a Tertiary Level Hospital in India.
Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Routine blood parameters of dengue infected children and adults. A meta-analysis.Pathogens and global health · 2023Pooled it
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- Severe dengue in adults admitted to intensive care units on réunion island: clinical spectrum, outcomes, and predictors of mortality.Critical care (London, England) · 2025Article
- Global estimation of dengue disability weights based on clinical manifestations data.Infectious diseases of poverty · 2025Article
- Dengue Fever:Sultan Qaboos University medical journal · 2025Article
- Excessive fluid resuscitation is associated with intensive care unit mortality in Pakistani patients with dengue shock syndrome.Acute and critical care · 2025Article
- Dengue and Scrub Typhus Co-infection at a Tertiary Care Centre in Nepal: A Case Series in Pediatric Patients.JNMA; journal of the Nepal Medical Association · 2025Article
- Urgent Alert: Potential Risk of Dengue Infection Transmission Through Blood Transfusion in Iran.Archives of Iranian medicine · 2024Review
- Correlation between CRP and ferritin in dengue patients: A hospital-based prospective observational study.Journal of family medicine and primary care · 2024Article
- Clinical Profile of Dengue Seropositive Infection From a Tertiary Care Hospital Situated in Mysuru, South India.Cureus · 2024Article
- Prevalence, Characteristics, and Outcomes Associated with Acute Kidney Injury among Adult Patients with Severe Dengue in Mainland China.The American journal of tropical medicine and hygiene · 2023Article
- Mechanism of Immune Evasion in Mosquito-Borne Diseases.Pathogens (Basel, Switzerland) · 2023Review
- Look Out for Fever: Clinical Profile of Dengue in Young Adults in a Tertiary Care Center in North India.Journal of laboratory physicians · 2023Article
- Predictors of Mortality in Patients With Dengue Fever: Insights From a Comparative Analysis.Cureus · 2023Article
- A modified Sequential Organ Failure Assessment score for dengue: development, evaluation and proposal for use in clinical trials.BMC infectious diseases · 2022Observational
- Article
- Rescue therapy with intravenous immunoglobulin in severe refractory dengue: A pilot study.Medical journal, Armed Forces India · 2022Article
- Viral characteristics and clinical presentation in dengue co-infection- Findings from a facility based observational study in Odisha, India.Journal of family medicine and primary care · 2021Article
- Maternal and fetal outcomes of dengue fever in pregnancy: a large prospective and descriptive observational study.Archives of gynecology and obstetrics · 2021Observational
- Predictors and Outcomes of Dengue-Associated Acute Kidney Injury.The American journal of tropical medicine and hygiene · 2021Review
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIndia is one of the seven identified countries in South-East Asia region regularly reporting dengue fever (DF)/dengue hemorrhagic fever (DHF) outbreaks. Even though the dengue prodrome and evolution of illness are most often similar in many patients, progress and outcome may differ significantly depending on the severity of illness as well as treatment instituted. We studied the clinical manifestations, outcome and factors predicting mortality of serology confirmed dengue fever cases admitted in Multidisciplinary Intensive Care Unit (MICU) of a high acuity healthcare facility in India. METHODOLOGY: All patients with serology proven dengue fever admitted to MICU between 1st July 2015 and1st December 2015 were included in the study. Clinical presentation, laboratory findings, severity of illness scores and outcome were recorded.
resultsMajority of the patients (58.4%) belonged to 21-40 year age group. Hepatic (96.8%) followed by hematological (79.2%) involvement were the most common findings. CNS involvement observed among 27%. Survival to hospital discharge was 78.9%. Respiratory and gastrointestinal system involvement was associated with increased mortality. Acute respiratory distress syndrome (ARDS), acute kidney injury (AKI) and shock were the clinical syndromes associated with mortality. Serum lactate, aspartate transaminase (AST) and alanine transaminase (ALT) were significantly elevated among non survivors. Significant difference in sequential organ failure assessment (SOFA) and acute physiology and chronic health evaluation (APACHE) scores was also observed among survivors and non survivors.
conclusionOrgan system involvement and higher disease severity scores are strong predictors of mortality. High index of suspicion for atypical manifestations of dengue is warranted. HOW TO CITE THIS ARTICLE: Padyana M, Karanth S, Vaidya S, Gopaldas JA. Clinical Profile and Outcome of Dengue Fever in Multidisciplinary Intensive Care Unit of a Tertiary Level Hospital in India. Indian J Crit Care Med 2019;23(6):270-273.
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