ReviewRadiologia brasileira
Ultrasound elastography in the evaluation of thyroid nodules: evolution of a promising diagnostic tool for predicting the risk of malignancy.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Diagnostic value of contrast-enhanced ultrasound combined with other imaging techniques in differentiating benign and malignant thyroid nodules: a network meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Quantitative Ultrasound Grayscale Analysis and Size of Benign and Malignant Solid Thyroid Nodules.Tomography (Ann Arbor, Mich.) · 2025Article
- Renal cell carcinoma metastasis to the thyroid gland after drug-induced thyroid dysfunction: case report.Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2025Article
- Shear wave elastography for thyroid nodule evaluation in patients with chronic autoimmune thyroiditis.Endocrine · 2025Observational
- Role of Ultrasound Elastography and Contrast-Enhanced Ultrasound (CEUS) in Diagnosis and Management of Malignant Thyroid Nodules-An Update.Diagnostics (Basel, Switzerland) · 2025Review
- Application of color doppler ultrasound and US shear wave elastography with connective tissue growth factor in the risk assessment of papillary thyroid carcinoma.BMC medical imaging · 2024Article
- Bubble nucleation and dynamics in acoustic droplet vaporization: a review of concepts, applications, and new directions.Zeitschrift fur medizinische Physik · 2023Review
- Ultrasound Elastography in Children.Children (Basel, Switzerland) · 2023Review
- Fundamentals of Bowel Cancer for Biomedical Engineers.Annals of biomedical engineering · 2023Review
- The Role of Shear Wave Elastography in the Discrimination Between Malignant and Benign Thyroid Nodules.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2020Article
- Article
- Shear wave elastography and Doppler ultrasound in kidney transplant recipients.Radiologia brasileiraArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The elastic properties of tissue have always been of interest in clinical practice. In the past, the identification of structures that were stiffer on physical palpation would raise the suspicion that "there was something wrong". With the development and advancement of medicine, there proved to be a true correlation in the prediction of malignancy of a lesion: malignant disease tends to stiffen the affected tissue, either by increased cell proliferation or fibrosis. Palpation is the oldest method for the detection of thyroid nodules, which is informed by the knowledge that malignant thyroid lesions tend to be much harder than benign ones. Unfortunately, palpation is a highly subjective method that is dependent on the size and location of the lesion, as well as on the skill of the physician. In cases where these nodules are very small or are located in deep regions, their detection by palpation is difficult or even impossible. In addition, although a malignant lesion differs in terms of elasticity, it may not have echogenic properties, preventing its detection by conventional ultrasound. Imaging that indicates the stiffness or deformation of tissues, through the use of ultrasound elastography techniques, adds new information related to their structural formation. In this article, we review the basic physical principles of elastography and the evolution of the method for the evaluation of thyroid nodules, as well as the limitations of and future perspectives for its use.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.