ArticleJournal of atherosclerosis and thrombosis2020
The Incidence and Associated Factors of Sudden Death in Patients on Hemodialysis: 10-Year Outcome of the Q-Cohort Study.
Article in Journal of atherosclerosis and thrombosis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Predictive role of C-reactive protein in sudden death: a meta-analysis of prospective studies.The Journal of international medical research · 2022Pooled it
- Ankle-brachial index rather than brachial-ankle pulse wave velocity is associated with cognitive function in older adults undergoing incident hemodialysis: a multicentre cross-sectional study.Annals of medicine · 2026Article
- A systematic review and meta-analysis and mendelian randomization analysis of serum phosphorus, albumin, and CRP as risk factors for death in hemodialysis patients.Journal of medical biochemistry · 2026Article
- Review
- Computed Tomography Evaluation of Extracellular Volume for Predicting Prognosis in Patients with Severe Renal Dysfunction on Dialysis.Journal of clinical medicine · 2024Article
- Oral Frailty as a Risk Factor for Malnutrition and Sarcopenia in Patients on Hemodialysis: A Prospective Cohort Study.Nutrients · 2024Observational
- Association between glycated albumin and sudden death in patients undergoing hemodialysis.Clinical and experimental nephrology · 2024Article
- Association Between Disturbed Serum Phosphorus Levels and QT Interval Prolongation.Kidney international reports · 2024Article
- Impact of Electrocardiographic Parameters on Sudden Death in Patients Receiving Maintenance Hemodialysis: Ten-Year Outcomes of the Q-Cohort Study.Journal of atherosclerosis and thrombosis · 2024Observational
- Left Ventricular Hypertrophy Geometry and Vascular Calcification Co-Modify the Risk of Cardiovascular Mortality in Patients with End-Stage Kidney Disease: A Retrospective Cohort Study.Journal of atherosclerosis and thrombosis · 2023Article
- Association of Hyperkalemia and Hypokalemia with Patient Characteristics and Clinical Outcomes in Japanese Hemodialysis (HD) Patients.Journal of clinical medicine · 2023Article
- Serum Alkaline Phosphatase Levels and Increased Risk of Brain Hemorrhage in Hemodialysis Patients: The Q-Cohort Study.Journal of atherosclerosis and thrombosis · 2022Article
- Sex differences in the 10-year survival of patients undergoing maintenance hemodialysis in the Q-Cohort Study.Scientific reports · 2022Observational
- Low Free Triiodothyronine Level as a Predictor of Cardiovascular Events and All-Cause Mortality in Patients Undergoing Hemodialysis: The DREAM Cohort.Journal of atherosclerosis and thrombosis · 2021Article
- Causes of death in patients undergoing maintenance hemodialysis in Japan: 10-year outcomes of the Q-Cohort Study.Clinical and experimental nephrology · 2021Observational
- Is Stiffness Parameter β Useful for the Evaluation of Atherosclerosis?~ Its Clinical Implications, Limitations, and Future Perspectives ~.Journal of atherosclerosis and thrombosis · 2021Review
- Impact of Multivascular Disease on Cardiovascular Mortality and Morbidity in Patients Receiving Hemodialysis: Ten-Year Outcomes of the Q-Cohort Study.Journal of atherosclerosis and thrombosis · 2021Article
- Sudden Death, A Common Cause of Death in Japanese Hemodialysis Patients.Journal of atherosclerosis and thrombosis · 2020Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe incidence of sudden death and its risk factors in patients on hemodialysis remain unclear. This study aimed to clarify the incidence of sudden death and its risk factors in Japanese patients on hemodialysis.
methodsA total of 3505 patients on hemodialysis aged ≥ 18 years were followed for 10 years. Multivariate-adjusted hazard ratio (HR) with 95% confidence interval (95% CI) of each risk factor of sudden death were calculated using a Cox proportional hazards model.
resultsDuring the 10-year follow-up, 1735 patients died, including 227 (13%) sudden deaths. The incidence rate of sudden death was 9.13 per 1000 person-years. In multivariable-adjusted Cox analysis, male sex (HR 1.67; 95% CI 1.20-2.33), age (HR 1.44; 95% CI 1.26-1.65 per 10-year higher), the presence of diabetes (HR 2.45; 95% CI 1.82-3.29), history of cardiovascular disease (HR 1.85; 95% CI 1.38-2.46), cardiothoracic ratio (HR 1.21; 95% CI 1.07-1.39 per 5% higher), serum C-reactive protein (HR 1.11; 95% CI 1.03-1.20 per 1-mg/dL higher), and serum phosphate (HR 1.15; 95% CI 1.03-1.30 per 1-mg/dL higher) were independent predictors of sudden death. A subgroup analysis stratified by sex or age showed that lower serum corrected calcium levels, not using vitamin D receptor activators in women, and a shorter dialysis session length in men or older people (≥ 65 years) increased the risk for sudden death.
conclusionsThis study clarified the incidence of sudden death and its specific predictors in Japanese patients on hemodialysis.
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