Evidence map›Paper›PMID 31434797›Full record

ArticleAging2019

LINC00511 promotes the malignant phenotype of clear cell renal cell carcinoma by sponging microRNA-625 and thereby increasing cyclin D1 expression.

Huanghao Deng, Changkun Huang, Yinhuai Wang, Hongyi Jiang, Shuang Peng, Xiaokun Zhao

Open access · greenAbstract read
In one paragraph

Article in Aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Crucial Roles of miR-625 in Human Cancer.Frontiers in medicine · 2022
    Review
  10. Review
  11. Article
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Huanghao DengDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China.
Changkun HuangDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China.
Yinhuai WangDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China.
Hongyi JiangDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China.
Shuang PengDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China.
Xiaokun ZhaoDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P.R. China.
Central South University · CNSecond Xiangya Hospital of Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The expression pattern and detailed roles of long noncoding RNA LINC00511 in clear cell renal cell carcinoma (ccRCC) remain unknown. We measured LINC00511 expression in ccRCC. We clarified the clinical characteristics associated with LINC00511 in ccRCC. We examined the biological roles of LINC00511 in the progression of ccRCC, and we identified the potential mechanisms involved. LINC00511 was upregulated in ccRCC tissues and cell lines. High LINC00511 expression significantly correlated with TNM classification, lymph node metastasis, and short overall survival among patients with ccRCC. Additionally, LINC00511 knockdown restricted ccRCC cell proliferation, colony formation, and metastasis

Indexed as

AgedCarcinoma, Renal CellCell Line, TumorCell ProliferationCyclin D1Disease ProgressionFemaleGene Expression Regulation, NeoplasticHumansKidney NeoplasmsLymphatic MetastasisMaleMicroRNAsMiddle AgedPhenotypeRNA, Long NoncodingCyclin D1MicroRNAsMIRN625 microRNA, humanRNA, Long Noncodingclear cell renal cell carcinomacyclin D1LINC00511microRNA-625

Identifiers

PMID31434797
PMCPMC6738417
OpenAlexW2969899955

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.