Evidence map›Paper›PMID 31434794›Full record

ArticleLife science alliance2019

Plasmalogen loss caused by remodeling deficiency in mitochondria.

Tomohiro Kimura, Atsuko K Kimura, Mindong Ren, Vernon Monteiro, Yang Xu, Bob Berno, Michael Schlame, Richard M Epand

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 43 citations in OpenAlex.

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  14. Mechanisms of mitochondrial respiratory adaptation.Nature reviews. Molecular cell biology · 2022
    Review
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  16. Dysfunctional peroxisomal lipid metabolisms and their ocular manifestations.Frontiers in cell and developmental biology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Tomohiro KimuraDepartment of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Canada kimurat@mcmaster.ca.ORCID 0000-0002-4192-7852
Atsuko K KimuraDepartment of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Canada.
Mindong RenDepartment of Cell Biology, New York University Langone Medical Center, New York, NY, USA.
Vernon MonteiroDepartment of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Canada.
Yang XuDepartment of Anesthesiology, New York University Langone Medical Center, New York, NY, USA.
Bob BernoDepartment of Chemistry and Chemical Biology, McMaster University, Hamilton, Canada.
Michael SchlameDepartment of Cell Biology, New York University Langone Medical Center, New York, NY, USA.
Richard M EpandDepartment of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Canada epand@mcmaster.ca.ORCID 0000-0002-9602-9558
McMaster University · CANYU Langone Health · US

Funding

Aberrant Cardiolipin Dynamics in Barth Syndrome - Renewal - 1R01GM115593 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SCHLAME, MICHAEL · 2015 to 2023
$2.9M
NIGMS NIH HHS R01 GM115593
6 · The paper itself

Abstract

Lipid homeostasis is crucial in human health. Barth syndrome (BTHS), a life-threatening disease typically diagnosed with cardiomyopathy and neutropenia, is caused by mutations in the mitochondrial transacylase tafazzin. By high-resolution

Indexed as

AcyltransferasesAnimalsBarth SyndromeCardiolipinsCardiomyopathiesFemaleHumansMaleMiceMice, Inbred C57BLMice, TransgenicMitochondriaMitochondrial MembranesPlasmalogensTranscription FactorsAcyltransferasesCardiolipinscholine plasmalogensphosphatidal ethanolaminesPlasmalogenstafazzin protein, mouseTranscription Factors

Identifiers

PMID31434794
PMCPMC6707388
OpenAlexW2969836417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.