Evidence map›Paper›PMID 31434769›Full record

Observational studyBMJ open2019

Antibiotic knowledge, attitudes and practices: new insights from cross-sectional rural health behaviour surveys in low-income and middle-income South-East Asia.

Marco J Haenssgen, Nutcha Charoenboon, Giacomo Zanello, Mayfong Mayxay, Felix Reed-Tsochas, Yoel Lubell, Heiman Wertheim, Jeffrey Lienert, Thipphaphone Xayavong, Yuzana Khine Zaw and 16 more

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03241316 (Antibiotics and Activity Spaces), which is not on this map. Cited by 55 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03241316 completednot on this map

Antibiotics and Activity Spaces: An Exploratory Study of Behaviour, Marginalisation, and Knowledge Diffusion

TypeobservationalSponsorUniversity of OxfordRan2017 to 2018Enrolled5,885ConditionsAntibiotic Use, Rural Healthcare-seeking Behaviour, Marginalisation (Economic, Social, Spatial)ArmsObservational study of behaviour
3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Marco J HaenssgenCenter for Tropical Medicine and Global Health, University of Oxford Centre for Tropical Medicine, Oxford, UK marco.haenssgen@warwick.ac.uk.ORCID 0000-0002-5849-7131
Nutcha CharoenboonMathematical/Economic Modelling, Mahidol Oxford Tropical Medicine Research Unit, Bangkok, Thailand.
Giacomo ZanelloSchool of Agriculture, Policy and Development, University of Reading, Reading, UK.
Mayfong MayxayLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Mahidol Oxford Tropical Medicine Research Unit, Vientiane, Laos.
Felix Reed-TsochasGreen Templeton College, Oxford, United Kingdom.ORCID 0000-0001-7923-750X
Yoel LubellCenter for Tropical Medicine and Global Health, University of Oxford Centre for Tropical Medicine, Oxford, UK.
Heiman WertheimMedical Microbiology Department, Radbuod University, Nijmegen, The Netherlands.
Jeffrey LienertGreen Templeton College, Oxford, United Kingdom.
Thipphaphone XayavongDepartment of Peace and Conflict Studies, University for Peace, Ciudad Colon, Costa Rica.
Yuzana Khine ZawDepartment of Global Health and Development, London School of Hygiene and Tropical Medicine, London, UK.
Amphayvone ThepkhamkongLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Mahidol Oxford Tropical Medicine Research Unit, Vientiane, Laos.
Nicksan SithongdengLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Mahidol Oxford Tropical Medicine Research Unit, Vientiane, Laos.
Nid KhamsoukthavongLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Mahidol Oxford Tropical Medicine Research Unit, Vientiane, Laos.
Chanthasone PhanthavongLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Mahidol Oxford Tropical Medicine Research Unit, Vientiane, Laos.
Somsanith BoualaisengLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Mahidol Oxford Tropical Medicine Research Unit, Vientiane, Laos.
Souksakhone VongsavangLao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit, Mahidol Oxford Tropical Medicine Research Unit, Vientiane, Laos.
Kanokporn WibunjakMathematical/Economic Modelling, Mahidol Oxford Tropical Medicine Research Unit, Bangkok, Thailand.
Poowadon Chai-InMathematical/Economic Modelling, Mahidol Oxford Tropical Medicine Research Unit, Bangkok, Thailand.
Patthanan ThavethanutthanawinMathematical/Economic Modelling, Mahidol Oxford Tropical Medicine Research Unit, Bangkok, Thailand.
Thomas AlthausCenter for Tropical Medicine and Global Health, University of Oxford Centre for Tropical Medicine, Oxford, UK.
Rachel Claire GreerMathematical/Economic Modelling, Mahidol Oxford Tropical Medicine Research Unit, Bangkok, Thailand.ORCID 0000-0001-9327-0234
Supalert NedsuwanPrimary Care Department, Chiangrai Regional Hospital, Chiang Rai, Thailand.
Tri WangrangsimakulChiangrai Clinical Research Unit, Chiangrai Regional Hospital, Chiang Rai, Thailand.
Direk LimmathurotsakulMicrobiology, Mahidol Oxford Tropical Medicine Research Unit, Bangkok, Thailand.ORCID 0000-0001-7240-5320
Elizabeth ElliottUCL Anthropology, University College London, London, UK.
Proochista ArianaCenter for Tropical Medicine and Global Health, University of Oxford Centre for Tropical Medicine, Oxford, UK.

Funding

Wellcome Trust
6 · The paper itself

Abstract

introductionLow-income and middle-income countries (LMICs) are crucial in the global response to antimicrobial resistance (AMR), but diverse health systems, healthcare practices and cultural conceptions of medicine can complicate global education and awareness-raising campaigns. Social research can help understand LMIC contexts but remains under-represented in AMR research.

objectiveTo (1) Describe antibiotic-related knowledge, attitudes and practices of the general population in two LMICs. (2) Assess the role of antibiotic-related knowledge and attitudes on antibiotic access from different types of healthcare providers.

designObservational study: cross-sectional rural health behaviour survey, representative of the population level.

settingGeneral rural population in Chiang Rai (Thailand) and Salavan (Lao PDR), surveyed between November 2017 and May 2018.

participants2141 adult members (≥18 years) of the general rural population, representing 712 000 villagers. OUTCOME MEASURES: Antibiotic-related knowledge, attitudes and practices across sites and healthcare access channels.

findingsVillagers were aware of antibiotics (Chiang Rai: 95.7%; Salavan: 86.4%; p<0.001) and drug resistance (Chiang Rai: 74.8%; Salavan: 62.5%; p<0.001), but the usage of technical concepts for antibiotics was dwarfed by local expressions like 'anti-inflammatory medicine' in Chiang Rai (87.6%; 95% CI 84.9% to 90.0%) and

conclusionsLocally specific conceptions and counterintuitive practices around antimicrobials can complicate AMR communication efforts and entail unforeseen consequences. Overcoming 'knowledge deficits' alone will therefore be insufficient for global AMR behaviour change. We call for an expansion of behavioural AMR strategies towards 'AMR-sensitive interventions' that address context-specific upstream drivers of antimicrobial use (eg, unemployment insurance) and complement education and awareness campaigns. TRIAL REGISTRATION NUMBER: Clinicaltrials.gov identifier NCT03241316.

Indexed as

Drug Resistance, MicrobialHealth Knowledge, Attitudes, PracticeAdultAnti-Bacterial AgentsCross-Sectional StudiesFemaleHumansLaosMaleRural PopulationSurveys and QuestionnairesThailandAnti-Bacterial Agentsantibioticsantimicrobial resistanceawarenessdevelopment studiesinterdisciplinary researchLao pdrsocial sciencessurveyThailandtreatment-seeking behaviour

Identifiers

PMID31434769
PMCPMC6707701

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.