SynthesisBMJ open2019
Impact of depression on clinical outcomes following percutaneous coronary intervention: a systematic review and meta-analysis.
Synthesis in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Depression and health outcomes: An umbrella review of systematic reviews and meta-analyses of observational studies.Translational psychiatry · 2025Pooled it
- Randomized trial of early exercise rehabilitation and its effects on patients with acute coronary syndrome.Scientific reports · 2024Trial
- Beyond the Usual Suspects: A Narrative Review of High-Yield Non-Traditional Risk Factors for Atherosclerosis.Journal of clinical medicine · 2026Review
- Symptom Burden in Patients with Acute Coronary Syndrome After Percutaneous Coronary Intervention: A Network and Latent Profile Analysis.Patient preference and adherence · 2026Article
- Coronary Artery Revascularization in the Older Adult Population: A Scientific Statement From the American Heart Association.Circulation · 2025Review
- Heterogeneity in medical coping modes and the moderating role of social support on social disability in patients after percutaneous coronary intervention.Frontiers in psychology · 2025Article
- Age, Creatinine, and Ejection Fraction (ACEF) Score is Associated with the Presence of Depression and Anxiety Symptoms in PCI Patients.Neuropsychiatric disease and treatment · 2025Article
- Resilience and its influencing factors after emergency percutaneous coronary intervention in young and middle-aged patients with first acute myocardial infarction.Scientific reports · 2024Article
- Predictors of Psychological Distress among Post-Operative Cardiac Patients: A Narrative Review.Healthcare (Basel, Switzerland) · 2023Review
- Construction and Validation of a Nomogram Predicting Depression Risk in Patients with Acute Coronary Syndrome Undergoing Coronary Stenting: A Prospective Cohort Study.Journal of cardiovascular development and disease · 2023Article
- Depression Following Acute Coronary Syndrome: A Review.Reviews in cardiovascular medicine · 2023Review
- Assessment and Management of Older Adults Undergoing PCI, Part 1: AJACC. Advances · 2023Article
- Primary PCI and Mental Health: A 12-Month Follow-Up Study.Healthcare (Basel, Switzerland) · 2023Article
- Mental Health of the Russian Federation Population versus Regional Living Conditions and Individual Income.International journal of environmental research and public health · 2023Article
- The prognostic study of mental stress-induced myocardial ischemia in coronary revascularization patients with depression/anxiety: rationale and design.BMC cardiovascular disorders · 2023Article
- Impact of mental disorders on clinical outcomes of physical diseases: an umbrella review assessing population attributable fraction and generalized impact fraction.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2023Article
- Assessment of Depression and Adherence to Guideline-Directed Medical Therapies Following Percutaneous Coronary Intervention.JAMA network open · 2022Article
- Metacognitive Short-Term Intervention in Patients With Mental Disorders Following Cardiovascular Events.Frontiers in psychiatry · 2022Article
- The association between self-reported health status and adverse events: a comparison among coronary artery bypass grafting (CABG) versus percutaneous coronary intervention (PCI).Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe objective of this meta-analysis was to assess whether depression in percutaneous coronary intervention (PCI) patients is associated with higher risk of adverse outcomes.
designSystematic review and meta-analysis.
methodsEMBASE, PubMed, CINAHL and PsycINFO were searched as data sources. We selected prospective cohort studies evaluating the relationship between depression and any adverse medical outcome, including all-cause mortality, cardiac mortality and non-fatal events, from inception to 28 February 2019. Two reviewers independently extracted information and calculated the risk of cardiovascular events in patients with preoperative or postoperative depression compared with non-depressed patients.
resultsEight studies (n=3297) met our inclusion criteria. Most studies found a positive association between depression and adverse cardiovascular outcomes. Meta-analysis yielded an aggregate risk ratio of 1.57 (95% CI 1.28 to 1.92, p<0.0001) for the magnitude of the relation between depression and adverse outcomes.
conclusionsOur systematic review and meta-analysis suggests that depression is associated with an increased risk of worse clinical outcome or mortality in patients undergoing PCI. Assessment time and length of follow-up do not have a significant effect on this conclusion.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.