Evidence map›Paper›PMID 31434744›Full record

ArticlemSphere2019

Posttranslational Regulation of IL-23 Production Distinguishes the Innate Immune Responses to Live Toxigenic versus Heat-Inactivated Vibrio cholerae.

Ana A Weil, Crystal N Ellis, Meti D Debela, Taufiqur R Bhuiyan, Rasheduzzaman Rashu, Daniel L Bourque, Ashraful I Khan, Fahima Chowdhury, Regina C LaRocque, Richelle C Charles and 4 more

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Frontiers in medicine · 2023
    Review
  5. Article
  6. Correlates of Protection for Cholera.The Journal of infectious diseases · 2021
    Article
  7. Systemic, Mucosal, and Memory Immune Responses following Cholera.Tropical medicine and infectious disease · 2021
    Review
  8. Article
  9. mSphere · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Ana A Weil *Infectious Diseases Division, Massachusetts General Hospital, Boston, Massachusetts, USA.
Crystal N Ellis *Infectious Diseases Division, Massachusetts General Hospital, Boston, Massachusetts, USA.
Meti D DebelaInfectious Diseases Division, Massachusetts General Hospital, Boston, Massachusetts, USA.
Taufiqur R BhuiyanInfectious Diseases Division, International Center for Diarrheal Disease and Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Rasheduzzaman RashuInfectious Diseases Division, International Center for Diarrheal Disease and Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Daniel L BourqueInfectious Diseases Division, Massachusetts General Hospital, Boston, Massachusetts, USA.
Ashraful I KhanInfectious Diseases Division, International Center for Diarrheal Disease and Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Fahima ChowdhuryInfectious Diseases Division, International Center for Diarrheal Disease and Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Regina C LaRocqueInfectious Diseases Division, Massachusetts General Hospital, Boston, Massachusetts, USA.
Richelle C CharlesInfectious Diseases Division, Massachusetts General Hospital, Boston, Massachusetts, USA.
Edward T RyanInfectious Diseases Division, Massachusetts General Hospital, Boston, Massachusetts, USA.
Stephen B CalderwoodInfectious Diseases Division, Massachusetts General Hospital, Boston, Massachusetts, USA.
Firdausi QadriInfectious Diseases Division, International Center for Diarrheal Disease and Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
Jason B HarrisDepartment of Medicine, Harvard Medical School, Boston, Massachusetts, USA jbharris@mgh.harvard.edu.
Harvard University · USInternational Centre for Diarrhoeal Disease Research · BDMassachusetts General Hospital · US

Funding

INFECTIOUS DISEASE AND BASIC MICROBIOLOGICAL MECHANISMST32AI007061 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Marcia B Goldberg · 1985 to 2026
$12.1M
Training program in vaccine development and public healthD43TW005572 · FIC · MASSACHUSETTS GENERAL HOSPITAL · PI QADRI, FIRDAUSI, RYAN, EDWARD T. · 2000 to 2025
$5.4M
O-Specific Polysaccharide Responses and CholeraR37AI106878 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Edward T. Ryan · 2020 to 2026
$5.1M
Innate and early B cell responses to V. choleraeR01AI103055 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HARRIS, JASON B · 2014 to 2018
$3.9M
O-Specific Polysaccharide Responses and CholeraR01AI106878 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI RYAN, EDWARD T. · 2014 to 2018
$3.7M
The gut microbiome and susceptibility to Vibrio choleraeK08AI123494 · NIAID · UNIVERSITY OF WASHINGTON · PI WEIL, ANA A · 2016 to 2020
$967k
Humoral and adaptive immune responses study in Vibrio cholerae infectionK43TW010362 · FIC · INTERNATIONAL CTR/DIARRHOEAL DIS RES · PI BHUIYAN, MD TAUFIQUR RAHMAN · 2016 to 2020
$359k
FIC NIH HHS D43 TW005572FIC NIH HHS K43 TW010362NIAID NIH HHS K08 AI123494NIAID NIH HHS R01 AI103055NIAID NIH HHS R01 AI106878NIAID NIH HHS R37 AI106878NIAID NIH HHS T32 AI007061
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Immunity, InnateAntibodies, BacterialAntigens, BacterialCholera ToxinCholera VaccinesCytokinesGene Expression RegulationHot TemperatureHumansInterleukin-23 Subunit p19MonocytesRNA Processing, Post-TranscriptionalTHP-1 CellsVaccines, InactivatedVaccines, Live, UnattenuatedVibrio choleraeAntibodies, BacterialAntigens, BacterialCholera ToxinCholera VaccinesCytokinesIL23A protein, humanInterleukin-23 Subunit p19Vaccines, InactivatedVaccines, Live, UnattenuatedcholeraIL-23Vibrio cholerae

Identifiers

PMID31434744
PMCPMC6706466
OpenAlexW2969659361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.