Evidence map›Paper›PMID 31434726›Full record

ArticleJournal of clinical microbiology2019

Increased Clinical Specificity with Ultrasensitive Detection of Clostridioides difficile Toxins: Reduction of Overdiagnosis Compared to Nucleic Acid Amplification Tests.

Johanna Sandlund, Joel Estis, Phoebe Katzenbach, Niamh Nolan, Kirstie Hinson, Jennifer Herres, Troy Pero, Gwyn Peterson, Jeung-Mi Schumaker, Craig Stevig and 3 more

Open access · bronzeAbstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Emerging Diagnostics inInternational journal of molecular sciences · 2024
    Review
  4. Article
  5. Hindsight Is 2019-the Year in Clinical Microbiology.Clinical microbiology newsletter · 2020
    Article
  6. Review
  7. Article
  8. Article
  9. The Role of Diagnostic Stewardship inCurrent infectious disease reports · 2020
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Johanna SandlundSingulex, Inc., Alameda, California, USA.
Joel EstisSingulex, Inc., Alameda, California, USA.
Phoebe KatzenbachSingulex, Inc., Alameda, California, USA.
Niamh NolanSingulex, Inc., Alameda, California, USA.
Kirstie HinsonDepartment of Microbiology, Laboratories Northwest, MultiCare Health System, Tacoma, Washington, USA.
Jennifer HerresDepartment of Microbiology, Laboratories Northwest, MultiCare Health System, Tacoma, Washington, USA.
Troy PeroDepartment of Microbiology, Laboratories Northwest, MultiCare Health System, Tacoma, Washington, USA.
Gwyn PetersonDepartment of Microbiology, Laboratories Northwest, MultiCare Health System, Tacoma, Washington, USA.
Jeung-Mi SchumakerDepartment of Microbiology, Laboratories Northwest, MultiCare Health System, Tacoma, Washington, USA.
Craig StevigDepartment of Microbiology, Laboratories Northwest, MultiCare Health System, Tacoma, Washington, USA.
Rhonda WarrenDepartment of Microbiology, Laboratories Northwest, MultiCare Health System, Tacoma, Washington, USA.
Tsubasa WestDepartment of Microbiology, Laboratories Northwest, MultiCare Health System, Tacoma, Washington, USA.
Siu-Kei ChowDepartment of Microbiology, Laboratories Northwest, MultiCare Health System, Tacoma, Washington, USA jacky.chow@multicare.org.
MultiCare Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedBacteriological TechniquesClostridioides difficileClostridium InfectionsEnterotoxinsFecesFemaleHumansImmunoassayMaleMedical OveruseMiddle AgedNucleic Acid Amplification TechniquesSensitivity and SpecificitySingle Molecule ImagingEnterotoxinsC. difficilesingle-molecule counting technologyultrasensitivity

Identifiers

PMID31434726
PMCPMC6813012
OpenAlexW2969954347

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.