Evidence map›Paper›PMID 31434724›Full record

ArticleJournal of clinical microbiology2019

Ultrasensitive Detection of Clostridioides difficile Toxins in Stool by Use of Single-Molecule Counting Technology: Comparison with Detection of Free Toxin by Cell Culture Cytotoxicity Neutralization Assay.

Glen Hansen, Stephen Young, Alan H B Wu, Emily Herding, Vickie Nordberg, Ray Mills, Christen Griego-Fullbright, Aaron Wagner, Chui Mei Ong, Shawna Lewis and 5 more

Open access · bronzeAbstract readComparative StudyMulticenter StudyValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 1 country.

Glen HansenDepartment of Pathology, Hennepin County Medical Center, Minneapolis, Minnesota, USA.
Stephen YoungTriCore Reference Laboratories, Albuquerque, New Mexico, USA.
Alan H B WuDepartment of Laboratory Medicine, University of California, Zuckerberg San Francisco General Hospital, San Francisco, California, USA.
Emily HerdingDepartment of Pathology, Hennepin County Medical Center, Minneapolis, Minnesota, USA.
Vickie NordbergDepartment of Pathology, Hennepin County Medical Center, Minneapolis, Minnesota, USA.
Ray MillsTriCore Reference Laboratories, Albuquerque, New Mexico, USA.
Christen Griego-FullbrightTriCore Reference Laboratories, Albuquerque, New Mexico, USA.
Aaron WagnerTriCore Reference Laboratories, Albuquerque, New Mexico, USA.
Chui Mei OngDepartment of Laboratory Medicine, University of California, Zuckerberg San Francisco General Hospital, San Francisco, California, USA.
Shawna LewisDivision of Medical Microbiology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Joseph YoonDivision of Medical Microbiology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Joel EstisSingulex, Inc., Alameda, California, USA.
Johanna SandlundSingulex, Inc., Alameda, California, USA.
Emily FriedlandSingulex, Inc., Alameda, California, USA.
Karen C CarrollDivision of Medical Microbiology, Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA kcarrol7@jhmi.edu.
Applied Research Associates (United States) · USJohns Hopkins Medicine · USSan Francisco General Hospital · USUniversity of Minnesota · USHennepin County Medical Center · USJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laboratory tests for

Indexed as

AdolescentAdultAgedBacteriological TechniquesChildChild, PreschoolClostridioides difficileClostridium InfectionsCytotoxicity Tests, ImmunologicEnterotoxinsFecesFemaleHumansImmunoenzyme TechniquesMaleMiddle AgedEnterotoxinsC. difficilesingle-molecule counting technologytoxins A and Bultrasensitiveultrasensitivity

Identifiers

PMID31434724
PMCPMC6812992
OpenAlexW2969765965

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.