Evidence map›Paper›PMID 31434692›Full record

ArticleBioscience reports2019

LINC00511 is associated with the malignant status and promotes cell proliferation and motility in cervical cancer.

Chun-Ling Yu, Xiao-Ling Xu, Fang Yuan

Open access · goldAbstract read
In one paragraph

Article in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  14. LINC00511 promotes cervical cancer progression by regulating the miR-497-5p/MAPK1 axis.Apoptosis : an international journal on programmed cell death · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Long noncoding RNACell cycle (Georgetown, Tex.) · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Chun-Ling YuDepartment of Gynaecology, Daqing Oilfield General Hospital, Daqing, Heilongjiang 163000, China.
Xiao-Ling XuDepartment of Gynaecology, Rizhao Central Hospital, Rizhao, Shandong 7963622, China.
Fang YuanDepartment of Gynecology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, China ycling2019@163.com.ORCID 0000-0002-7194-1583
Daqing Oilfield General Hospital · CNPeople’s Hospital of Rizhao · CNQingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

LINC00511 is a newly identified lncRNA that is up-regulated in many types of human cancers and may serve as an oncogenic lncRNA. However, there was no report about the role of LINC00511 in cervical cancer. Therefore, we investigated the clinical value of LINC00511 in cervical cancer patients via analyzing the correlation between LINC00511 expression and clinicopathological features. Moreover, we performed loss-of-function study to estimate the effect of LINC00511 on cervical cancer cell proliferation, migration, and invasion. In our study, we found LINC00511 expression levels were increased in cervical cancer tissues and cell lines compared with adjacent normal tissues and normal cervical epithelial cell line, respectively. High LINC00511 expression was correlated with advanced clinical stage, large tumor size, histological type of adenocarcinoma, and present lymph node metastasis, distant metastasis, and poor overall survival in cervical cancer patients. The

Indexed as

Biomarkers, TumorCarcinogenesisCell Line, TumorCell MovementCell ProliferationFemaleGene Expression Regulation, NeoplasticHumansLymphatic MetastasisMiddle AgedNeoplasm InvasivenessNeoplasm StagingRNA, Long NoncodingUterine Cervical NeoplasmsBiomarkers, TumorRNA, Long Noncodingbiomarkercervical cancerLINC00511lncRNA

Identifiers

PMID31434692
PMCPMC6744586
OpenAlexW2970748229

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.