ArticleGenome research2019
Exploration of fine-scale recombination rate variation in the domestic horse.
Article in Genome research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 35 citations in OpenAlex.
- Article
- An increased number of heterozygous calls in the AxiomTM Equine Genotyping Array.G3 (Bethesda, Md.) · 2026Article
- A Minimal Hybrid Sterility Genome Assembled by Chromosome Swapping Between Mouse Subspecies (Mus musculus).Molecular biology and evolution · 2024Article
- Analyses of whole-genome sequences from 185 North American Thoroughbred horses, spanning 5 generations.Scientific reports · 2024Article
- Exploration of Genome-Wide Recombination Rate Variation Patterns at Different Scales in Pigs.Animals : an open access journal from MDPI · 2024Article
- Predicted genetic burden and frequency of phenotype-associated variants in the horse.Scientific reports · 2024Article
- Recombination hotspots in soybean [Glycine max (L.) Merr.].G3 (Bethesda, Md.) · 2023Article
- Selection signature analyses and genome-wide association reveal genomic hotspot regions that reflect differences between breeds of horse with contrasting risk of degenerative suspensory ligament desmitis.G3 (Bethesda, Md.) · 2022Article
- AAnimals : an open access journal from MDPI · 2022Article
- Runs of homozygosity in Sable Island feral horses reveal the genomic consequences of inbreeding and divergence from domestic breeds.BMC genomics · 2022Article
- Article
- High-Resolution Estimates of Crossover and Noncrossover Recombination from a Captive Baboon Colony.Genome biology and evolution · 2022Article
- Genetic diversity and selection in Puerto Rican horses.Scientific reports · 2022Article
- Adaptive Control of the Meiotic Recombination Landscape by DNA Site-dependent Hotspots With Implications for Evolution.Frontiers in genetics · 2022Article
- Genetic Variation and the Distribution of Variant Types in the Horse.Frontiers in genetics · 2021Article
- A genome-wide scan for candidate lethal variants in Thoroughbred horses.Scientific reports · 2020Article
- Genetic Variability in the Italian Heavy Draught Horse from Pedigree Data and Genomic Information.Animals : an open access journal from MDPI · 2020Article
- Genetic Diversity and Signatures of Selection in a Native Italian Horse Breed Based on SNP Data.Animals : an open access journal from MDPI · 2020Article
- Equine recombination map updated to EquCab3.0.Animal genetics · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Total genetic map length and local recombination landscapes typically vary within and across populations. As a first step to understanding the recombination landscape in the domestic horse, we calculated population recombination rates and identified likely recombination hotspots using approximately 1.8 million SNP genotypes for 485 horses from 32 distinct breeds. The resulting breed-averaged recombination map spans 2.36 Gb and accounts for 2939.07 cM. Recombination hotspots occur once per 23.8 Mb on average and account for ∼9% of the physical map length. Regions with elevated recombination rates in the entire cohort were enriched for genes in pathways involving interaction with the environment: immune system processes (specifically, MHC class I and class II genes), responses to stimuli, and serotonin receptor pathways. We found significant correlations between differences in local recombination rates and population differentiation quantified by
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.