Evidence map›Paper›PMID 31434256›Full record

ArticleMolecules (Basel, Switzerland)2019

Determination of Flavonoid Glycosides by UPLC-MS to Authenticate Commercial Lemonade.

Ying Xue, Lin-Sen Qing, Li Yong, Xian-Shun Xu, Bin Hu, Ming-Qing Tang, Jing Xie

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ying XueSchool of Pharmacy, Chengdu Medical College, Chengdu 610500, China.
Lin-Sen QingChengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.ORCID 0000-0002-9685-9180
Li YongSichuan Provincial Center for Disease Control and Prevention, Chengdu 610041, China.
Xian-Shun XuSichuan Provincial Center for Disease Control and Prevention, Chengdu 610041, China.
Bin HuSichuan Provincial Center for Disease Control and Prevention, Chengdu 610041, China.
Ming-Qing TangSchool of Pharmacy, Chengdu Medical College, Chengdu 610500, China.
Jing XieSchool of Pharmacy, Chengdu Medical College, Chengdu 610500, China. xiejing@cmc.edu.cn.
Chinese Academy of Sciences · CNSichuan Center for Disease Control and Prevention · CNChengdu Medical College · CN

Funding

the West Light Foundation of The Chinese Academy of Sciences 2018XBZG_XBQNXZ_A_005
6 · The paper itself

Abstract

So far, there is no report on the quality evaluation of lemonade available in the market. In this study, a sample preparation method was developed for the determination of flavonoid glycosides by ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) based on vortex-assisted dispersive liquid-liquid microextraction. First, potential flavonoids in lemonade were scanned and identified by ultra-performance liquid chromatography-time of flight mass spectrometry (UPLC-TOF/MS). Five flavonoid glycosides were identified as eriocitrin, narirutin, hesperidin, rutin, and diosmin according to the molecular formula provided by TOF/MS and subsequent confirmation of the authentic standard. Then, an ultra-performance liquid chromatography-triple quadrupole mass spectrometry (UPLC-QqQ/MS) method was developed to determine these five flavonoid glycosides in lemonade. The results showed that the content of rutin in some lemonade was unreasonably high. We suspected that many illegal manufacturers achieved the goal of low-cost counterfeiting lemonade by adding rutin. This suggested that it was necessary for relevant departments of the state to make stricter regulations on the quality standards of lemonade beverages.

Indexed as

BeveragesChromatography, LiquidCitrusFlavonoidsFood AnalysisFood ContaminationGlycosidesLiquid Phase MicroextractionMass SpectrometryFlavonoidsGlycosidescounterfeiting lemonadeflavonoid glycosideUPLC-MSvortex-assisted dispersive liquid-liquid microextraction

Identifiers

PMID31434256
PMCPMC6719059
OpenAlexW2969701033

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.