ArticlePharmaceutics2019
Nanolipid-Trehalose Conjugates and Nano-Assemblies as Putative Autophagy Inducers.
Article in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 15 citations in OpenAlex.
- Exploring the Potential of Herbal Compounds as Autophagy Modulators in Alzheimer's Disease: A Comprehensive Review.CNS & neurological disorders drug targets · 2026Review
- Trehalose-Bearing Carriers to Target Impaired Autophagy and Protein Aggregation Diseases.Journal of medicinal chemistry · 2023Review
- Tetraphenylethylene-Based Photoluminescent Self-Assembled Nanoparticles: Preparation and Biological Evaluation.ACS medicinal chemistry letters · 2023Article
- A Perspective on Missing Aspects in Ongoing Purification Research towardsFoods (Basel, Switzerland) · 2023Review
- Cannabidiol as Self-Assembly Inducer for Anticancer Drug-Based Nanoparticles.Molecules (Basel, Switzerland) · 2022Article
- Folic acid functionalization for targeting self-assembled paclitaxel-based nanoparticles.RSC advances · 2022Article
- Squalene-Based Nano-Assemblies Improve the Pro-Autophagic Activity of Trehalose.Pharmaceutics · 2022Article
- Trehalose-Based Nucleolipids as Nanocarriers for Autophagy Modulation: An In Vitro Study.Pharmaceutics · 2022Article
- Review
- New Class of Betulinic Acid-Based Nanoassemblies of Cabazitaxel, Podophyllotoxin, and Thiocolchicine.ACS medicinal chemistry letters · 2020Article
- Natural Compounds and Autophagy: Allies Against Neurodegeneration.Frontiers in cell and developmental biology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The disaccharide trehalose is an autophagy inducer, but its pharmacological application is severely limited by its poor pharmacokinetics properties. Thus, trehalose was coupled via suitable spacers with squalene (in 1:2 and 1:1 stoichiometry) and with betulinic acid (1:2 stoichiometry), in order to yield the corresponding nanolipid-trehalose conjugates
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.