Evidence map›Paper›PMID 31433930›Full record

Trial reportThe New England journal of medicine2019

Fornix-Region Deep Brain Stimulation-Induced Memory Flashbacks in Alzheimer's Disease.

Wissam Deeb, Bryan Salvato, Leonardo Almeida, Kelly D Foote, Robert Amaral, Jurgen Germann, Paul B Rosenberg, David F Tang-Wai, David A Wolk, Anna D Burke and 7 more

Open access · greenAbstract readLetterRandomized Controlled Trial
In one paragraph

Trial report in The New England journal of medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 54 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Biomarker changes associated with fornix deep brain stimulation in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Brain stimulation and elicited memories.Acta neurochirurgica · 2023
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 10 institutions in 2 countries.

Wissam DeebUniversity of Florida, Gainesville, FL wissam.deeb@neurology.ufl.edu.
Bryan SalvatoFlorida State University, Tallahassee, FL.
Leonardo AlmeidaUniversity of Florida, Gainesville, FL.
Kelly D FooteUniversity of Florida, Gainesville, FL.
Robert AmaralDouglas Mental Health University Research Institute, Montreal, QC, Canada.
Jurgen GermannDouglas Mental Health University Research Institute, Montreal, QC, Canada.
Paul B RosenbergJohns Hopkins University, Baltimore, MD.
David F Tang-WaiUniversity of Toronto, Toronto, ON, Canada.
David A WolkUniversity of Pennsylvania, Philadelphia, PA.
Anna D BurkeBarrow Neurological Institute, Phoenix, AZ.
Stephen SallowayAlpert Medical School of Brown University, Providence, RI.
Marwan N SabbaghCleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV.
M Mallar ChakravartyDouglas Mental Health University Research Institute, Montreal, QC, Canada.
Gwenn S SmithJohns Hopkins University School of Medicine, Baltimore, MD.
Constantine G LyketsosJohns Hopkins University, Baltimore, MD.
Andres M LozanoUniversity of Toronto, Toronto, ON, Canada.
Michael S OkunUniversity of Florida, Gainesville, FL.
University of Florida · USDouglas Mental Health University Institute · CAJohns Hopkins University · USUniversity of Toronto · CABarrow Neurological Institute · USBrown University · USCleveland Clinic · USFlorida State University · USJohns Hopkins Medicine · USUniversity of Pennsylvania · US

Funding

Research Education ComponentP30AG066507 · NIA · JOHNS HOPKINS UNIVERSITY · PI MARILYN S. ALBERT · 2020 to 2026
$29.3M
Exploring the relationship between cerebral glucose metabolism and change in cognition in the ADvance randomized control trial of Deep Brain StimulationR01AG042165 · NIA · JOHNS HOPKINS UNIVERSITY · PI LOZANO, ANDRES M., LYKETSOS, CONSTANTINE G · 2012 to 2016
$2.8M
NIA NIH HHS P30 AG066507NIA NIH HHS R01 AG042165NIA NIH HHS R01AG042165
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Deep Brain StimulationFornix, BrainMemoryAlzheimer DiseaseCorpus CallosumHumansMale

Identifiers

PMID31433930
PMCPMC7313538
OpenAlexW2969937195

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.